Plot no 105, Part A, Karnataka Industrial Area Development Board, Humnabad, Karnataka 585330

API Job Work & Contract Manufacturing in Karnataka

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Explore our specialized Contract Manufacturing & API Job Work services. We offer end-to-end custom synthesis, scale-up, and GMP-compliant production in India.

API Custom Manufacturing Facility
CDMO & JOB WORK

Your Trusted Partner for
Custom Manufacturing

Kalpasthana Life Care Products is a GMP-compliant API job work and contract manufacturing company based in Humnabad, Karnataka. We serve pharmaceutical companies across India — from Hyderabad, Bengaluru, and Mumbai — providing reliable pharma job work on custom molecules, existing APIs, and bulk drug intermediates.

Our CDMO services in India cover the complete manufacturing lifecycle: from custom synthesis and route scouting at lab scale to full commercial-scale API production in our dedicated Humnabad plant. Whether you need dedicated pharmaceutical job work in Karnataka or a long-term contract manufacturing partner for API intermediates, we deliver technical expertise and regulatory compliance.

Our facility is equipped with GLR and SSR reactors (500L to 5,000L), in-house HPLC/GC analytical labs, and a pilot plant — making us one of the few small CDMO companies in Karnataka capable of handling complex multi-step chemistries including Grignard, Friedel-Crafts, and high-temperature condensation reactions at commercial scale.

Custom Synthesis
Process Scale-Up
IP Protection
Tech Transfer
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Core CDMO Services

Comprehensive solutions spanning from process development to high-volume commercial manufacturing.

Process R&D

Route scouting, process optimization, and yield enhancement. We refine complex lab-scale processes, utilizing DoE to ensure robustness, purity, and cost-efficiency prior to commercial scale-up.

Commercial Scale-Up

Seamless transition from pilot plant to multi-ton commercial production. Dedicated blocks equipped with GLR and SSR reactors handle aggressive and multi-step synthesis safely.

Tech Transfer

We operate under stringent Non-Disclosure Agreements (NDAs). Our dedicated tech transfer teams ensure that your proprietary formulations and IP remain completely secure.

ADVANCED CHEMISTRY

Specialized Reactions

Our facility and team of experts are equipped to safely handle a wide spectrum of complex chemistries and hazardous reagents.

Friedel-Crafts Alkylation & Halogenation

Handling anhydrous aluminum chloride and other Lewis acids under strictly controlled moisture-free environments, alongside specialized containment systems for executing chlorination and bromination processes safely at bulk scale.

Nitration & Reduction

Controlled handling of nitric acid mixtures, followed by catalytic hydrogenation or chemical reduction techniques.

Grignard Reactions

Large-scale preparation and safe execution of organomagnesium compounds under inert nitrogen atmospheres.

Condensation Synthesis

High-yield multi-step condensation processes requiring precise temperature control and prolonged reflux operations.

High-Temp Chemistry

Thermic fluid systems capable of sustaining high-temperature reactions up to 250°C consistently over prolonged cycles.

Advanced Infrastructure & QA

GMP-compliant facilities designed to consistently meet stringent global regulatory standards.

GLR & SSR Reactors

From 500L pilot scales to 5,000L commercial capacities, offering unmatched versatility.

GMP Documentation

Complete batch traceability, exhaustive SOPs, and validation protocols ensuring audit readiness.

Analytical Precision

In-house QA/QC labs equipped with state-of-the-art HPLC, GC, and wet analysis setups.

Sustainable EHS

Robust effluent treatment plants (ETP) and comprehensive worker safety protocols.

WHO WE SERVE

Industries & Clients We Partner With

We provide API job work and custom synthesis to pharmaceutical manufacturers, API producers, and chemical companies across India.

API Manufacturers

Pharma companies needing API job work on carbazole, cyclohexanedione, and hydrazine chemistry. We handle synthesis you cannot do in-house.

Research Institutions

Universities and R&D organizations needing custom synthesis of specific intermediates in kilogram quantities for clinical or research programs.

Export-Oriented Pharma

Companies exporting Ondansetron, Carvedilol, and Frovatriptan APIs to regulated markets who need a reliable Indian KSM and intermediate partner.

HOW WE WORK

Our Contract Manufacturing Process

A clear 4-step journey from your initial query to GMP-certified commercial delivery.

1
Technical Discussion

Share your target molecule, route, and volume requirements. We sign an NDA before reviewing any proprietary information.

2
Lab-Scale Trial

We execute a small-batch synthesis trial in our analytical lab, provide COA and HPLC data, and confirm feasibility before scale-up.

3
Pilot Scale-Up

We scale the process to our 500L–1,000L pilot reactors. Process parameters, yield, and purity are locked before moving to commercial volumes.

4
Commercial Delivery

GMP-certified batch production in 5,000L reactors with full documentation — COA, MSDS, batch records — dispatched to your facility across India.

COMMON INQUIRIES

Frequently Asked Questions

Find answers to standard technical questions about our manufacturing infrastructure, IP protection, and custom synthesis capabilities.

Our facility features state-of-the-art Glass-Lined Reactors (GLR) and Stainless Steel Reactors (SSR) ranging from 500L (ideal for process R&D and pilot scale-ups) up to 5,000L commercial capacities, offering maximum flexibility for B2B bulk chemical production.
IP protection is a core pillar of our CDMO services. We execute binding Non-Disclosure Agreements (NDAs) prior to receiving target files. All reaction routes, process parameters, and batch logs are stored securely, ensuring that proprietary formulations remain completely confidential and secure.
Our chemical synthesis plant regularly handles complex chemistries at scale. Our specialties include Friedel-Crafts alkylations/acylations, halogenations (chlorination/bromination), controlled nitration, catalytic reduction, Grignard reactions, and prolonged high-temperature reflux condensation up to 250°C.
Yes, all contract manufacturing operations are conducted in GMP-compliant plants in Humnabad, Karnataka. We implement exhaustive SOPs, run rigorous QA/QC wet labs equipped with HPLC/GC analyzers, and maintain complete batch records for absolute traceability and regulatory compliance.
For standard API job work on molecules within our existing chemistry expertise (carbazole, cyclohexanedione, and hydrazine derivatives), the minimum batch size starts at 25 kg. For new custom molecules requiring process development, we begin with lab-scale trials (50 g – 1 kg) before agreeing on a commercial MOQ. We are flexible for long-term partnership agreements.
Yes. We are an established manufacturer of key intermediates for Ondansetron (9-Methyl Carbazolone, 1,2,3,9-Tetrahydrocarbazolone) and Carvedilol (4-Hydroxycarbazole, 1,2,3,9-Tetrahydrocarbazolone, Phenyl Hydrazine Hydrochloride). Pharma companies can source these on a job work basis or partner with us for dedicated batch production under a supply agreement.
For known molecules within our chemistry portfolio, the typical timeline is: NDA & Technical review (1–3 days) → Lab trial (7–14 days) → Pilot scale-up (2–4 weeks) → First commercial batch (4–8 weeks). For new custom molecules requiring full process development, timelines are discussed after an initial feasibility assessment. We prioritize transparent communication throughout.
We supply API job work and contract-manufactured chemicals across India — primarily to pharmaceutical hubs in Hyderabad (Telangana), Bengaluru (Karnataka), Mumbai (Maharashtra), Ahmedabad (Gujarat), and Delhi NCR. International export to South Asian and global pharma companies can be arranged with appropriate regulatory documentation.
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We are a leading API intermediate manufacturer in India, committed to delivering top-quality pharmaceutical and healthcare solutions globally.

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