1,4-Cyclohexanedione (1,4-CHD / 14 CHD)
Manufacturer of 1,4-Cyclohexanedione Essential Cyclic Intermediate for Frovatriptan Synthesis and Conductive Polymers. (CAS 637-88-7).
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Manufacturer of 1,4-Cyclohexanedione Essential Cyclic Intermediate for Frovatriptan Synthesis and Conductive Polymers. (CAS 637-88-7).
Request a Quote
1,4-Cyclohexanedione is a symmetric alicyclic diketone intermediate highly valued in organic synthesis and specialty chemical manufacturing. It serves as a vital key starting material (KSM) for the anti-migraine drug Frovatriptan. Its bifunctional structure allows for highly selective mono- or di-functionalization, making it critical for the synthesis of advanced pharmaceutical intermediates, specialty liquid crystals, and conductive polymers. Kalpasthana, as a trusted Fine Chemical Manufacturer, guarantees consistent batch purity and optimized moisture controls to ensure highest reaction yields for industrial chemical applications.
Manufacturing Importance: Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.
Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.
1,4-Cyclohexanedione is a symmetric, bifunctional building block highly valued in organic synthesis. It is the primary key starting material (KSM) for the anti-migraine drug Frovatriptan. Its unique diketone reactivity enables selective mono- or di-functionalization, making it essential in synthesizing conductive polymers, liquid crystals, agricultural crop-protection agents, and pharmaceutical materials.
Within active pharmaceutical ingredient (API) synthesis, 1,4-cyclohexanedione is particularly valuable for its ability to undergo selective reductive amination at one carbonyl group while keeping the second carbonyl available for further heterocyclic assembly, a key chemical pathway required to construct the pyrrolidine ring structure of triptan-class therapeutics.
Pivotal starting material for constructing the tetrahydrocarbazole core of Frovatriptan API.
Precursor for synthesizing conductive polyaniline/quinone composites and advanced liquid crystal displays (LCDs).
Allows elegant double condensation, reductive amination, or selective protection for complex heterocyclic syntheses.
For 1,4-Cyclohexanedione, quality is our foundational pillar. We ensure high-purity diketone footprints through strict process controls, specialized ketone synthesis lines, and rigorous isomer separation techniques. Our facility monitors reactions to minimize trace cyclohexanone and related polymer impurities, guaranteeing batch consistency for sensitive anti-migraine API synthesis.
Every shipment is backed by in-house GC-FID purity verification (maintaining assay purity >=99.0= ), moisture content checks, and standard COA profiles to streamline client compliance and warehouse storage validation.
Manufactured under strict GMP-compliant standard operating procedures.
In-house analytical testing ensuring HPLC purity >=99.0= for every batch.
Complete B2B regulatory paperwork, technical dossiers, and audit support.
Manufactured under strict GMP-compliant standard operating procedures.
In-house analytical testing ensuring HPLC purity >=99.0= for every batch.
Complete B2B regulatory paperwork, technical dossiers, and audit support.
1,4-Cyclohexanedione (14CHD) is a symmetrical cyclic diketone. It is synthesized by the Dieckmann condensation of dimethyl succinate to form dimethyl succinyl succinate (DMSS), followed by hydrolysis and subsequent decarboxylation. Alternatively, it can be produced via the selective hydrogenation of hydroquinone. It forms a white to light yellow crystalline solid.
1,4-Cyclohexanedione is a highly versatile building block in organic synthesis. It is used as an intermediate in the manufacture of liquid crystals for electronic displays, specialty polymers, and pharmaceutical actives. In medicinal chemistry, it serves as a precursor for various drug classes, including agents targeting GABA receptors and complex heterocyclic compounds.
Manufactured under rigid quality controls, our 1,4-Cyclohexanedione achieves a purity of >=99.0= by GC with minimal trace impurities.
Standard commercial packaging is 25 kg HDPE fiber drums, stored in tightly sealed containers in a cool, dry, and well-ventilated warehouse.
Standard laboratory PPE (gloves, safety glasses, dust masks) is recommended when handling the powder to avoid inhalation and skin contact.
HPLC purity verified at >=99.0= with minimal related substances.
Continuous commercial-scale volume manufacturing capacity.
Complete analytical profiles, GC profiles, MSDS, and COA dossiers.
Equipped with a 50 kL combined reactor volume in Karnataka.
Kalpasthana Life Care Products, Plot no 105, Part A, KIADB Industrial Area, Humnabad, Bidar District, Karnataka, India - 585330
GMP-compliant state-of-the-art facility, rigorous GC purity standards =98.0= .
Standard 25 kg HDPE fiber drums with double polythene inner bags; custom B2B packaging available.
Commercial Sourcing & Synonyms: For B2B procurement queries, this symmetrical diketone is cataloged under CAS No. 637-88-7. It is primarily utilized as a high-purity Frovatriptan intermediate in active pharmaceutical synthesis. Kalpasthana is an established Bulk Drug Intermediates supplier India, delivering certified quality batches globally.
1,4-Cyclohexanedione is a highly versatile alicyclic diketone. In pharmaceutical manufacturing, it serves as the essential intermediate for synthesizing Frovatriptan (a triptan drug for migraine relief). Its symmetrical bifunctional ketone structure also makes it a valuable building block for synthesizing conductive polymers, liquid crystals, and specialty organic materials.
We supply bulk 1,4-Cyclohexanedione with a GC purity of = 98.0% , appearing as a white to light-yellow crystalline powder. We implement strict moisture and volatiles control to prevent polymerization. Every batch is accompanied by comprehensive quality records including COAs and FTIR/GC spectra.
1,4-Cyclohexanedione is packed in standard 25 kg fiber drums or customized B2B packaging depending on order volume. Our state-of-the-art facility in Humnabad, Karnataka guarantees prompt domestic dispatch and reliable containerized shipping for export orders.
1,4-Cyclohexanedione is a symmetric alicyclic diketone intermediate highly valued in organic synthesis and specialty chemical manufacturing. It serves as a vital key starting material (KSM) for the anti-migraine drug Frovatriptan. Its bifunctional structure allows for highly selective mono- or di-functionalization, making it critical for the synthesis of advanced pharmaceutical intermediates, specialty liquid crystals, and conductive polymers. Kalpasthana, as a trusted Fine Chemical Manufacturer, guarantees consistent batch purity and optimized moisture controls to ensure highest reaction yields for industrial chemical applications.
Manufacturing Importance: Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.
1,4-Cyclohexanedione is a symmetric, bifunctional building block highly valued in organic synthesis. It is the primary key starting material (KSM) for the anti-migraine drug Frovatriptan. Its unique diketone reactivity enables selective mono- or di-functionalization, making it essential in synthesizing conductive polymers, liquid crystals, agricultural crop-protection agents, and pharmaceutical materials.
Within active pharmaceutical ingredient (API) synthesis, 1,4-cyclohexanedione is particularly valuable for its ability to undergo selective reductive amination at one carbonyl group while keeping the second carbonyl available for further heterocyclic assembly, a key chemical pathway required to construct the pyrrolidine ring structure of triptan-class therapeutics.
For 1,4-Cyclohexanedione, quality is our foundational pillar. We ensure high-purity diketone footprints through strict process controls, specialized ketone synthesis lines, and rigorous isomer separation techniques. Our facility monitors reactions to minimize trace cyclohexanone and related polymer impurities, guaranteeing batch consistency for sensitive anti-migraine API synthesis.
Every shipment is backed by in-house GC-FID purity verification (maintaining assay purity >=99.0= ), moisture content checks, and standard COA profiles to streamline client compliance and warehouse storage validation.
Manufactured under strict GMP-compliant standard operating procedures.
In-house analytical testing ensuring HPLC purity >=99.0= for every batch.
Complete B2B regulatory paperwork, technical dossiers, and audit support.
Global pharmaceutical sourcing teams partner with Kalpasthana due to our chemical manufacturing expertise, infrastructure reliability, and strict compliance alignment:
1,4-Cyclohexanedione (14CHD) is a symmetrical cyclic diketone. It is synthesized by the Dieckmann condensation of dimethyl succinate to form dimethyl succinyl succinate (DMSS), followed by hydrolysis and subsequent decarboxylation. Alternatively, it can be produced via the selective hydrogenation of hydroquinone. It forms a white to light yellow crystalline solid.
1,4-Cyclohexanedione is a highly versatile building block in organic synthesis. It is used as an intermediate in the manufacture of liquid crystals for electronic displays, specialty polymers, and pharmaceutical actives. In medicinal chemistry, it serves as a precursor for various drug classes, including agents targeting GABA receptors and complex heterocyclic compounds.
Manufactured under rigid quality controls, our 1,4-Cyclohexanedione achieves a purity of >=99.0= by GC with minimal trace impurities.
Standard commercial packaging is 25 kg HDPE fiber drums, stored in tightly sealed containers in a cool, dry, and well-ventilated warehouse.
Standard laboratory PPE (gloves, safety glasses, dust masks) is recommended when handling the powder to avoid inhalation and skin contact.
| Chemical Synonyms | Tetrahydro-p-benzoquinone, 1,4-Dioxocyclohexane, Cyclohexane-1,4-dione |
|---|---|
| Manufacturing Location | Kalpasthana Life Care Products, Plot no 105, Part A, KIADB Industrial Area, Humnabad, Bidar District, Karnataka, India - 585330 |
| Compliance & Quality | GMP-compliant state-of-the-art facility, rigorous GC purity standards =98.0= . |
| Commercial Packaging | Standard 25 kg HDPE fiber drums with double polythene inner bags; custom B2B packaging available. |
Commercial Sourcing & Synonyms: For B2B procurement queries, this symmetrical diketone is cataloged under CAS No. 637-88-7. It is primarily utilized as a high-purity Frovatriptan intermediate in active pharmaceutical synthesis. Kalpasthana is an established Bulk Drug Intermediates supplier India, delivering certified quality batches globally.
1,4-Cyclohexanedione is a highly versatile alicyclic diketone. In pharmaceutical manufacturing, it serves as the essential intermediate for synthesizing Frovatriptan (a triptan drug for migraine relief). Its symmetrical bifunctional ketone structure also makes it a valuable building block for synthesizing conductive polymers, liquid crystals, and specialty organic materials.
We supply bulk 1,4-Cyclohexanedione with a GC purity of = 98.0% , appearing as a white to light-yellow crystalline powder. We implement strict moisture and volatiles control to prevent polymerization. Every batch is accompanied by comprehensive quality records including COAs and FTIR/GC spectra.
1,4-Cyclohexanedione is packed in standard 25 kg fiber drums or customized B2B packaging depending on order volume. Our state-of-the-art facility in Humnabad, Karnataka guarantees prompt domestic dispatch and reliable containerized shipping for export orders.
We are a leading API intermediate manufacturer in India, committed to delivering top-quality pharmaceutical and healthcare solutions globally.