Plot no 105, Part A, Karnataka Industrial Area Development Board, Humnabad, Karnataka 585330

1,4-Cyclohexanedione (1,4-CHD / 14 CHD) Manufacturer India

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Manufacturer of 1,4-Cyclohexanedione (CAS 637-88-7). Essential Cyclic Intermediate for Frovatriptan Synthesis and Conductive Polymers.

Chemical Structure of 1,4-Cyclohexanedione

1,4-Cyclohexanedione (1,4-CHD / 14 CHD)

CAS No: 637-88-7

Essential Cyclic Intermediate for Frovatriptan Synthesis and Conductive Polymers.

An essential cyclic ketone intermediate (widely known as 1,4-CHD, 14 CHD, or Cyclohexane-1,4-dione) used in the synthesis of the migraine medication Frovatriptan and conductive polymers.

Serving as a critical building block for Frovatriptan and specialized agrochemicals, this compound is manufactured with high assay values. We ensure excellent stability and consistency for complex organic synthesis applications.

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Product Specifications

Product Name 1,4-Cyclohexanedione (1,4-CHD / 14 CHD)
Synonyms / Abbreviations 1,4-CHD, Cyclohexane-1,4-dione, 14 CHD, Tetrahydroquinone
CAS Number 637-88-7
Molecular Formula C6H8O2
Molecular Weight 112.13 g/mol
Appearance White to Light Yellow Crystalline Powder
Purity (GC) ≥ 98.0%
Melting Point 77°C - 81°C

Applications & Usage

1,4-Cyclohexanedione is a symmetric, bifunctional building block highly valued in organic synthesis. It is the primary key starting material (KSM) for the anti-migraine drug Frovatriptan. Its unique diketone reactivity enables selective mono- or di-functionalization, making it essential in synthesizing conductive polymers, liquid crystals, agricultural crop-protection agents, and pharmaceutical materials.

Key Features

  • Frovatriptan Synthesis: Pivotal starting material for constructing the tetrahydrocarbazole core of Frovatriptan API.
  • Conductive Materials & Polymers: Precursor for synthesizing conductive polyaniline/quinone composites and advanced liquid crystal displays (LCDs).
  • Bifunctional Reactivity: Allows elegant double condensation, reductive amination, or selective protection for complex heterocyclic syntheses.

Product Specifications & Procurement FAQs

Detailed quality specifications, compliance data, and procurement answers for pharma sourcing professionals.

Quality & Technical Specifications

Chemical Synonyms Tetrahydro-p-benzoquinone, 1,4-Dioxocyclohexane, Cyclohexane-1,4-dione
Manufacturing Location Kalpasthana Life Care Products, Plot no 105, Part A, KIADB Industrial Area, Humnabad, Bidar District, Karnataka, India - 585330
Compliance & Quality GMP-compliant state-of-the-art facility, rigorous GC purity standards ≥98.0%.
Commercial Packaging Standard 25 kg HDPE fiber drums with double polythene inner bags; custom B2B packaging available.

Frequently Asked Questions

What organic synthesis pathways utilize 1,4-Cyclohexanedione (CAS 637-88-7)?

1,4-Cyclohexanedione is a highly versatile alicyclic diketone. In pharmaceutical manufacturing, it serves as the essential intermediate for synthesizing Frovatriptan (a triptan drug for migraine relief). Its symmetrical bifunctional ketone structure also makes it a valuable building block for synthesizing conductive polymers, liquid crystals, and specialty organic materials.

What is the purity level and technical specification of Kalpasthana's bulk 1,4-Cyclohexanedione?

We supply bulk 1,4-Cyclohexanedione with a GC purity of ≥98.0%, appearing as a white to light-yellow crystalline powder. We implement strict moisture and volatiles control to prevent polymerization. Every batch is accompanied by comprehensive quality records including COAs and FTIR/GC spectra.

What are the industrial packaging and lead times for B2B procurement of 1,4-Cyclohexanedione?

1,4-Cyclohexanedione is packed in standard 25 kg fiber drums or customized B2B packaging depending on order volume. Our state-of-the-art facility in Humnabad, Karnataka guarantees prompt domestic dispatch and reliable containerized shipping for export orders.

Technical Profile & Sourcing Guide

Comprehensive chemical specs, catalytic pathways, and quality compliance guidelines for raw materials sourcing.

Chemical Synthesis

1,4-Cyclohexanedione (14CHD) is a symmetrical cyclic diketone. It is synthesized by the Dieckmann condensation of dimethyl succinate to form dimethyl succinyl succinate (DMSS), followed by hydrolysis and subsequent decarboxylation. Alternatively, it can be produced via the selective hydrogenation of hydroquinone. It forms a white to light yellow crystalline solid.

Applications & Pathways

1,4-Cyclohexanedione is a highly versatile building block in organic synthesis. It is used as an intermediate in the manufacture of liquid crystals for electronic displays, specialty polymers, and pharmaceutical actives. In medicinal chemistry, it serves as a precursor for various drug classes, including agents targeting GABA receptors and complex heterocyclic compounds.

Quality & Compliance

Manufactured under rigid quality controls, our 1,4-Cyclohexanedione achieves a purity of >=99.0% by GC with minimal trace impurities.

Storage & Packaging

Standard commercial packaging is 25 kg HDPE fiber drums, stored in tightly sealed containers in a cool, dry, and well-ventilated warehouse.

Safety & Protocols

Standard laboratory PPE (gloves, safety glasses, dust masks) is recommended when handling the powder to avoid inhalation and skin contact.

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