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Methyl 5-oxohexanoate

High-Purity Methyl 5-oxohexanoate (5-Oxo Methyl Hexanoate). A versatile, bifunctional keto-ester for organic synthesis and fine chemical development. (CAS 13984-50-4).

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Methyl 5-oxohexanoate CAS 13984-50-4 intermediate manufacturer India
Technical Specifications
Product Name
Methyl 5-oxohexanoate
Synonyms / Abbreviations
IUPAC & Chemical Names
5-Oxohexanoic acid methyl ester Methyl 5-oxocaproate 5-Oxo Methyl Ester Methyl 5-oxohexanoate (MOH) 5-oxohexanoic acid methyl ester (MOH) Aliphatic keto-ester Organic synthesis building block Methyl 5-oxohexanoate supplier
Common Names
MOH
Drug & Sourcing Names
Methyl 5-oxohexanoate API Intermediate Methyl 5-oxohexanoate Bulk Drug Methyl 5-oxohexanoate intermediate Valerolactone derivative Keto-ester bulk drug intermediate
CAS Number
13984-50-4
Molecular Formula
C7H12O3
Molecular Weight
144.17 g/mol
Appearance
Colorless to off-white liquid
Purity (GC)
≥ 98.0%
Boiling Point
204°C - 206°C
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Product Overview

Methyl 5-oxohexanoate is a versatile intermediate widely utilized in the synthesis of active pharmaceutical ingredients (APIs) and specialty organic compounds. Its dual-functional structure (retaining a reactive ketone and a protected ester group) enables regioselective condensations, notably in the synthesis of Indomethacin and other non-steroidal anti-inflammatory drugs (NSAIDs). As an experienced specialty chemical manufacturer in India, Kalpasthana ensures highly controlled process parameters to eliminate side-chain impurities, offering reliable bulk manufacturing and packaging options.

Manufacturing Importance: Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.

Manufacturing Importance

Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.

Applications & Industrial Relevance

The ester is a highly versatile intermediate utilized in the synthesis of active pharmaceutical ingredients, notably the non-steroidal anti-inflammatory drug (NSAID) Indomethacin. Its dual functionality allows for selective condensations, cyclizations, and preparation of pyridazinone cardiovascular agents, agrochemicals, and fragrance molecules.

In pharmaceutical manufacturing, this keto-ester acts as a versatile building block for the synthesis of nitrogen-containing heterocycles. Sourcing a high-purity product is essential, as the differential reactivity of the ketone and ester carbonyls allows for regioselective reactions that are critical in forming key structural links for indomethacin derivatives.

Indomethacin Synthesis

Critical starting material that reacts with 4-methoxyphenylhydrazine to form the indole core of Indomethacin.

Fine Chemical Scaffold

Excellent bifunctional reactivity combining a keto group and an ester for synthesizing pyrrole, pyridazine, and furan rings.

Fragrance & Agrochemicals

Used to synthesize delta-lactones, cyclic fragrance compounds, and select crop protection herbicides.

Quality Assurance & Process Control

For Methyl 5-oxohexanoate, quality is our foundational pillar. We ensure high-purity keto-ester footprints through strict process controls, moisture-monitored crystallization, and vacuum fractional distillation. Our facility specifically checks reaction temperatures to minimize ester hydrolysis and condensation side products, guaranteeing batch consistency for heterocyclic ring synthesis.

Every shipment is backed by in-house GC-FID purity verification (maintaining assay purity >=98.0%), low acidity checks, and standard COA profiles to support client B2B audits and regulatory compliance.

Manufactured under strict GMP-compliant standard operating procedures.

In-house analytical testing ensuring HPLC purity >=99.0% for every batch.

Complete B2B regulatory paperwork, technical dossiers, and audit support.

GMP Standards

Manufactured under strict GMP-compliant standard operating procedures.

HPLC Verification

In-house analytical testing ensuring HPLC purity >=99.0% for every batch.

Document Support

Complete B2B regulatory paperwork, technical dossiers, and audit support.

Technical Sourcing Profile

Chemical Synthesis

Methyl 5-oxohexanoate is a keto-ester. It is synthesized via the esterification of 5-oxohexanoic acid with methanol, or by the oxidation of cyclohexanone derivatives under catalytic conditions. It is a clear liquid with high chemical stability.

Applications & Pathways

The compound serves as an important intermediate in the synthesis of fine chemicals and pharmaceutical compounds. Its dual functionality (ester and ketone groups) allows for diverse chemical reactions, including condensation and alkylation.

Quality & Compliance

We supply Methyl 5-oxohexanoate with a purity of >=98.0% by GC. Complete batch analysis is provided to sourcing agents.

Storage & Packaging

It is stored in cool, well-ventilated areas in sealed steel containers to prevent moisture absorption.

Safety & Protocols

Sourcing professionals are provided with complete safety data sheets (SDS) and quality assurance guidelines for safe bulk handling.

Why Choose Kalpasthana?

High Purity Standards

HPLC purity verified at >=99.0% with minimal related substances.

Reliable Supply Chain

Continuous commercial-scale volume manufacturing capacity.

Robust Technical Support

Complete analytical profiles, GC profiles, MSDS, and COA dossiers.

Advanced Infrastructure

Equipped with a 50 kL combined reactor volume in Karnataka.

Sourcing Compliance & Synonyms

Chemical Synonyms

IUPAC & Chemical Names
5-Oxohexanoic acid methyl ester Methyl 5-oxocaproate 5-Oxo Methyl Ester Methyl 5-oxohexanoate (MOH) 5-oxohexanoic acid methyl ester (MOH) Aliphatic keto-ester Organic synthesis building block Methyl 5-oxohexanoate supplier
Common Names
MOH
Drug & Sourcing Names
Methyl 5-oxohexanoate API Intermediate Methyl 5-oxohexanoate Bulk Drug Methyl 5-oxohexanoate intermediate Valerolactone derivative Keto-ester bulk drug intermediate

Manufacturing Location

Kalpasthana Life Care Products, Humnabad, Bidar District, Karnataka, India - 585330

Compliance & Quality

GMP-compliant state-of-the-art facility, rigorous GC and analytical purity testing.

Commercial Packaging

Standard commercial HDPE drums or customized B2B bottles; custom packaging available.

Commercial Sourcing Note

Commercial Sourcing & Synonyms: Sourcing under CAS No. 13984-50-4 from an established custom chemical manufacturer ensures standard specifications. This keto-ester is a versatile organic synthesis building block used in pharmaceutical intermediates synthesis at Kalpasthana.

Frequently Asked Questions

What makes Methyl 5-oxohexanoate a useful synthetic building block?

Its main advantage lies in its orthogonal functional groups. The ketone can be reduced, alkylated, or condensed while keeping the ester group intact (or vice-versa), providing a flexible pathway for synthesizing complex organic compounds.

What are the standard shipping and storage conditions for Methyl 5-oxohexanoate?

It should be stored in a cool, well-ventilated area in tightly closed original containers. It is stable under standard transport conditions. MSDS and technical sheets are supplied with every order.

What packaging options are available for bulk orders of Methyl 5-oxohexanoate?

It is available in standard 200 kg steel/HDPE drums, as well as smaller 25 kg carboys. We can customize packaging to include nitrogen blanketing to ensure long-term stability and high assay values during shipping and warehousing.

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Methyl 5-oxohexanoate (CAS 13984-50-4) Manufacturer India

Home Products Methyl 5-oxohexanoate

High-Purity Methyl 5-oxohexanoate (5-Oxo Methyl Hexanoate). A versatile, bifunctional keto-ester for organic synthesis and fine chemical development.

Organic synthesis building block Methyl 5-oxohexanoate CAS 13984-50-4

Bulk Methyl 5-oxohexanoate CAS 13984-50-4 Supplier

CAS No: 13984-50-4

Methyl 5-oxohexanoate is a versatile intermediate utilized in the synthesis of Indomethacin and other active pharmaceutical ingredients. Sourced from our Karnataka manufacturing facility, it ensures high HPLC purity and low acid values for predictable reaction kinetics.

Product Overview

Methyl 5-oxohexanoate is a versatile intermediate widely utilized in the synthesis of active pharmaceutical ingredients (APIs) and specialty organic compounds. Its dual-functional structure (retaining a reactive ketone and a protected ester group) enables regioselective condensations, notably in the synthesis of Indomethacin and other non-steroidal anti-inflammatory drugs (NSAIDs). As an experienced specialty chemical manufacturer in India, Kalpasthana ensures highly controlled process parameters to eliminate side-chain impurities, offering reliable bulk manufacturing and packaging options.

Manufacturing Importance: Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.

Technical Specifications

Product Name Methyl 5-oxohexanoate
Synonyms / Alternate Names 5-Oxohexanoic acid methyl ester • Methyl 5-oxocaproate • 5-Oxo Methyl Ester • Methyl 5-oxohexanoate API Intermediate • Methyl 5-oxohexanoate Bulk Drug • Methyl 5-oxohexanoate (MOH) • MOH • Methyl 5-oxohexanoate intermediate • 5-oxohexanoic acid methyl ester (MOH) • Valerolactone derivative • Aliphatic keto-ester • Organic synthesis building block • Methyl 5-oxohexanoate supplier • Keto-ester bulk drug intermediate
CAS Number 13984-50-4
Molecular Formula C7H12O3
Molecular Weight 144.17 g/mol
Appearance Colorless to off-white liquid
Purity (GC) ≥ 98.0%
Boiling Point 204°C - 206°C
Request a Technical Quote Download Specs Sheet

Applications & Industrial Relevance

The ester is a highly versatile intermediate utilized in the synthesis of active pharmaceutical ingredients, notably the non-steroidal anti-inflammatory drug (NSAID) Indomethacin. Its dual functionality allows for selective condensations, cyclizations, and preparation of pyridazinone cardiovascular agents, agrochemicals, and fragrance molecules.

In pharmaceutical manufacturing, this keto-ester acts as a versatile building block for the synthesis of nitrogen-containing heterocycles. Sourcing a high-purity product is essential, as the differential reactivity of the ketone and ester carbonyls allows for regioselective reactions that are critical in forming key structural links for indomethacin derivatives.

Key Functionalities & Industrial Use Cases

  • Indomethacin Synthesis: Critical starting material that reacts with 4-methoxyphenylhydrazine to form the indole core of Indomethacin.
  • Fine Chemical Scaffold: Excellent bifunctional reactivity combining a keto group and an ester for synthesizing pyrrole, pyridazine, and furan rings.
  • Fragrance & Agrochemicals: Used to synthesize delta-lactones, cyclic fragrance compounds, and select crop protection herbicides.

Quality Assurance & Process Control

For Methyl 5-oxohexanoate, quality is our foundational pillar. We ensure high-purity keto-ester footprints through strict process controls, moisture-monitored crystallization, and vacuum fractional distillation. Our facility specifically checks reaction temperatures to minimize ester hydrolysis and condensation side products, guaranteeing batch consistency for heterocyclic ring synthesis.

Every shipment is backed by in-house GC-FID purity verification (maintaining assay purity >=98.0%), low acidity checks, and standard COA profiles to support client B2B audits and regulatory compliance.

GMP Standards

Manufactured under strict GMP-compliant standard operating procedures.

HPLC Verification

In-house analytical testing ensuring HPLC purity >=99.0% for every batch.

Document Support

Complete B2B regulatory paperwork, technical dossiers, and audit support.

Why Choose Kalpasthana?

Global pharmaceutical sourcing teams partner with Kalpasthana due to our chemical manufacturing expertise, infrastructure reliability, and strict compliance alignment:

  • High Purity Standards: HPLC purity verified at >=99.0% with minimal related substances.
  • Reliable Supply Chain: Continuous commercial-scale volume manufacturing capacity.
  • Robust Technical Support: Complete analytical profiles, GC profiles, MSDS, and COA dossiers.
  • Advanced Infrastructure: Equipped with a 50 kL combined reactor volume in Karnataka.

Technical Sourcing Profile

Chemical Synthesis

Methyl 5-oxohexanoate is a keto-ester. It is synthesized via the esterification of 5-oxohexanoic acid with methanol, or by the oxidation of cyclohexanone derivatives under catalytic conditions. It is a clear liquid with high chemical stability.

Applications & Pathways

The compound serves as an important intermediate in the synthesis of fine chemicals and pharmaceutical compounds. Its dual functionality (ester and ketone groups) allows for diverse chemical reactions, including condensation and alkylation.

Quality & Compliance

We supply Methyl 5-oxohexanoate with a purity of >=98.0% by GC. Complete batch analysis is provided to sourcing agents.

Storage & Packaging

It is stored in cool, well-ventilated areas in sealed steel containers to prevent moisture absorption.

Safety & Protocols

Sourcing professionals are provided with complete safety data sheets (SDS) and quality assurance guidelines for safe bulk handling.

Sourcing FAQs & Compliance Guide

Quality & Technical Specifications

Chemical Synonyms 5-Oxo methyl hexanoate, 5-Oxohexanoic acid methyl ester, Methyl 5-oxocaproate, Hexanoic acid, 5-oxo-, methyl ester, Methyl 5-oxohexanoate
Manufacturing Location Kalpasthana Life Care Products, Humnabad, Bidar District, Karnataka, India - 585330
Compliance & Quality GMP-compliant state-of-the-art facility, rigorous GC and analytical purity testing.
Commercial Packaging Standard commercial HDPE drums or customized B2B bottles; custom packaging available.

Commercial Sourcing & Synonyms: Sourcing under CAS No. 13984-50-4 from an established custom chemical manufacturer ensures standard specifications. This keto-ester is a versatile organic synthesis building block used in pharmaceutical intermediates synthesis at Kalpasthana.

Frequently Asked Questions

What makes Methyl 5-oxohexanoate a useful synthetic building block?

Its main advantage lies in its orthogonal functional groups. The ketone can be reduced, alkylated, or condensed while keeping the ester group intact (or vice-versa), providing a flexible pathway for synthesizing complex organic compounds.

What are the standard shipping and storage conditions for Methyl 5-oxohexanoate?

It should be stored in a cool, well-ventilated area in tightly closed original containers. It is stable under standard transport conditions. MSDS and technical sheets are supplied with every order.

What packaging options are available for bulk orders of Methyl 5-oxohexanoate?

It is available in standard 200 kg steel/HDPE drums, as well as smaller 25 kg carboys. We can customize packaging to include nitrogen blanketing to ensure long-term stability and high assay values during shipping and warehousing.

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