Methyl Adipoyl Chloride
High-Purity Methyl Adipoyl Chloride (Monomethyl Adipoyl Chloride). A premium ester acid chloride intermediate for selective organic synthesis and pharmaceutical manufacturing. (CAS 2110-39-6).
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High-Purity Methyl Adipoyl Chloride (Monomethyl Adipoyl Chloride). A premium ester acid chloride intermediate for selective organic synthesis and pharmaceutical manufacturing. (CAS 2110-39-6).
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Methyl Adipoyl Chloride (Methyl 5-(chlorocarbonyl)pentanoate) is an asymmetric, highly reactive acylating agent essential for the synthesis of Alpha Lipoic Acid. Sourcing from a reliable fine chemical manufacturer like Kalpasthana ensures that the moisture-sensitive acid chloride group is packaged under strict dry-nitrogen conditions to prevent hydrolysis. Our organic chemical synthesis processes are tightly monitored to provide excellent regioselectivity during chain extension and mono-acylation stages of commercial API production.
Manufacturing Importance: Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.
Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.
This acylating agent is a highly reactive asymmetric building block. It is the primary key intermediate for the commercial synthesis of Alpha Lipoic Acid (Thioctic Acid). The differential reactivity of the acid chloride end versus the protected methyl ester enables clean, selective mono-acylation and chain-extension reactions, making it vital in polymer modifying and API synthesis.
For the synthesis of Alpha Lipoic Acid, the asymmetric reactivity of Methyl Adipoyl Chloride is vital. The highly reactive acid chloride group is targeted for the initial carbon-carbon coupling, after which the protected methyl ester can be selectively hydrolyzed under basic conditions, ensuring high regioselectivity.
Reacts selectively with ethylene and sulfur compounds to construct the core structure of Alpha Lipoic Acid.
Highly reactive carbonyl chloride allows rapid coupling while the methyl ester remains intact for subsequent steps.
Used as an acylating agent to graft ester-terminated alkyl chains onto starch, cellulose, and high-performance polyamides.
For Methyl Adipoyl Chloride, quality is our foundational pillar. We ensure high-purity mono-acid chloride footprints through strict process controls, moisture-excluded glass-lined reactors, and vacuum distillation workflows. Our facility monitors chlorination parameters to minimize free adipoyl chloride and monomethyl adipate residues, guaranteeing batch consistency for Alpha Lipoic Acid synthesis.
Every commercial shipment of this moisture-sensitive acylating agent is backed by in-house GC-FID purity verification (maintaining assay purity >=98.0%), acidity checks, and standard COA profiles under dry nitrogen blanketing to ensure long-term stability.
Manufactured under strict GMP-compliant standard operating procedures.
In-house analytical testing ensuring HPLC purity >=99.0% for every batch.
Complete B2B regulatory paperwork, technical dossiers, and audit support.
Manufactured under strict GMP-compliant standard operating procedures.
In-house analytical testing ensuring HPLC purity >=99.0% for every batch.
Complete B2B regulatory paperwork, technical dossiers, and audit support.
Methyl Adipoyl Chloride (methyl 6-chloro-6-oxohexanoate) is a highly reactive acyl chloride. It is synthesized by the chlorination of monomethyl adipate using thionyl chloride or phosphorus trichloride, followed by vacuum distillation to ensure high purity and remove acidic gases. It is a moisture-sensitive, clear to light yellow liquid.
As a reactive acylating agent, this acid chloride is a key raw material in the multi-step synthesis of Alpha Lipoic Acid. The acyl chloride group undergoes rapid nucleophilic substitution, making it an essential building block for custom pharmaceuticals, peptides, and advanced polymer synthesis.
Sourced from our state-of-the-art facility, our Methyl Adipoyl Chloride maintains a purity of >=98.0% verified by GC.
It must be stored under a dry nitrogen blanket in specialized corrosion-resistant containers in a cool, dry area to maintain product integrity.
Since it reacts violently with water and moisture to release corrosive hydrochloric acid gas, strict isolation and acid-resistant PPE are mandatory.
HPLC purity verified at >=99.0% with minimal related substances.
Continuous commercial-scale volume manufacturing capacity.
Complete analytical profiles, GC profiles, MSDS, and COA dossiers.
Equipped with a 50 kL combined reactor volume in Karnataka.
Kalpasthana Life Care Products, Humnabad, Bidar District, Karnataka, India - 585330
GMP-compliant state-of-the-art facility, rigorous GC and analytical purity testing.
Standard commercial plastic carboys / glass bottles with moisture-tight seals or customized B2B packaging.
Commercial Sourcing & Synonyms: Sourcing Monomethyl adipoyl chloride under CAS No. 2110-39-6 ensures standard synthesis yields. This fine chemical intermediate is highly optimized for ALA synthesis (Alpha Lipoic Acid) at Kalpasthana's Humnabad facility.
Due to the differential reactivity between the highly reactive acid chloride group and the stable methyl ester. This allows chemists to selectively introduce the adipoyl moiety onto nucleophilic sites like amines or alcohols without side reactions or polymerization.
Methyl Adipoyl Chloride is moisture-sensitive and can release hydrogen chloride gas upon exposure to water or humidity. It must be stored in a cool, dry, well-ventilated area in tightly sealed, moisture-proof containers under dry nitrogen.
Every commercial batch of Methyl Adipoyl Chloride is shipped with a Certificate of Analysis (COA) specifying GC purity, a comprehensive Material Safety Data Sheet (MSDS), technical specifications sheets, and batch production records as requested for your regulatory filings.
Methyl Adipoyl Chloride (Methyl 5-(chlorocarbonyl)pentanoate) is an asymmetric, highly reactive acylating agent essential for the synthesis of Alpha Lipoic Acid. Sourcing from a reliable fine chemical manufacturer like Kalpasthana ensures that the moisture-sensitive acid chloride group is packaged under strict dry-nitrogen conditions to prevent hydrolysis. Our organic chemical synthesis processes are tightly monitored to provide excellent regioselectivity during chain extension and mono-acylation stages of commercial API production.
Manufacturing Importance: Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.
This acylating agent is a highly reactive asymmetric building block. It is the primary key intermediate for the commercial synthesis of Alpha Lipoic Acid (Thioctic Acid). The differential reactivity of the acid chloride end versus the protected methyl ester enables clean, selective mono-acylation and chain-extension reactions, making it vital in polymer modifying and API synthesis.
For the synthesis of Alpha Lipoic Acid, the asymmetric reactivity of Methyl Adipoyl Chloride is vital. The highly reactive acid chloride group is targeted for the initial carbon-carbon coupling, after which the protected methyl ester can be selectively hydrolyzed under basic conditions, ensuring high regioselectivity.
For Methyl Adipoyl Chloride, quality is our foundational pillar. We ensure high-purity mono-acid chloride footprints through strict process controls, moisture-excluded glass-lined reactors, and vacuum distillation workflows. Our facility monitors chlorination parameters to minimize free adipoyl chloride and monomethyl adipate residues, guaranteeing batch consistency for Alpha Lipoic Acid synthesis.
Every commercial shipment of this moisture-sensitive acylating agent is backed by in-house GC-FID purity verification (maintaining assay purity >=98.0%), acidity checks, and standard COA profiles under dry nitrogen blanketing to ensure long-term stability.
Manufactured under strict GMP-compliant standard operating procedures.
In-house analytical testing ensuring HPLC purity >=99.0% for every batch.
Complete B2B regulatory paperwork, technical dossiers, and audit support.
Global pharmaceutical sourcing teams partner with Kalpasthana due to our chemical manufacturing expertise, infrastructure reliability, and strict compliance alignment:
Methyl Adipoyl Chloride (methyl 6-chloro-6-oxohexanoate) is a highly reactive acyl chloride. It is synthesized by the chlorination of monomethyl adipate using thionyl chloride or phosphorus trichloride, followed by vacuum distillation to ensure high purity and remove acidic gases. It is a moisture-sensitive, clear to light yellow liquid.
As a reactive acylating agent, this acid chloride is a key raw material in the multi-step synthesis of Alpha Lipoic Acid. The acyl chloride group undergoes rapid nucleophilic substitution, making it an essential building block for custom pharmaceuticals, peptides, and advanced polymer synthesis.
Sourced from our state-of-the-art facility, our Methyl Adipoyl Chloride maintains a purity of >=98.0% verified by GC.
It must be stored under a dry nitrogen blanket in specialized corrosion-resistant containers in a cool, dry area to maintain product integrity.
Since it reacts violently with water and moisture to release corrosive hydrochloric acid gas, strict isolation and acid-resistant PPE are mandatory.
| Chemical Synonyms | Monomethyl adipoyl chloride, Methyl 5-(chlorocarbonyl)pentanoate, Adipic acid monomethyl ester chloride, Methyl adipoyl chloride, Methyl 6-chloro-6-oxohexanoate, Monomethyl adipate acid chloride, Adipoyl chloride monomethyl ester |
|---|---|
| Manufacturing Location | Kalpasthana Life Care Products, Humnabad, Bidar District, Karnataka, India - 585330 |
| Compliance & Quality | GMP-compliant state-of-the-art facility, rigorous GC and analytical purity testing. |
| Commercial Packaging | Standard commercial plastic carboys / glass bottles with moisture-tight seals or customized B2B packaging. |
Commercial Sourcing & Synonyms: Sourcing Monomethyl adipoyl chloride under CAS No. 2110-39-6 ensures standard synthesis yields. This fine chemical intermediate is highly optimized for ALA synthesis (Alpha Lipoic Acid) at Kalpasthana's Humnabad facility.
Due to the differential reactivity between the highly reactive acid chloride group and the stable methyl ester. This allows chemists to selectively introduce the adipoyl moiety onto nucleophilic sites like amines or alcohols without side reactions or polymerization.
Methyl Adipoyl Chloride is moisture-sensitive and can release hydrogen chloride gas upon exposure to water or humidity. It must be stored in a cool, dry, well-ventilated area in tightly sealed, moisture-proof containers under dry nitrogen.
Every commercial batch of Methyl Adipoyl Chloride is shipped with a Certificate of Analysis (COA) specifying GC purity, a comprehensive Material Safety Data Sheet (MSDS), technical specifications sheets, and batch production records as requested for your regulatory filings.
We are a leading API intermediate manufacturer in India, committed to delivering top-quality pharmaceutical and healthcare solutions globally.