Plot no 105, Part A, Karnataka Industrial Area Development Board, Humnabad, Karnataka 585330
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1,3-Cyclohexanedione (1,3-CHD)

High-quality 1,3-Cyclohexanedione (1,3-CHD / 13 CHD / Dihydroresorcinol, CAS 504-02-9), a key intermediate for pharmaceutical and agrochemical synthesis. (CAS 504-02-9).

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1,3-Cyclohexanedione (1,3-CHD) CAS 504-02-9 intermediate manufacturer India
Technical Specifications
Product Name
1,3-Cyclohexanedione (1,3-CHD)
Synonyms / Abbreviations
IUPAC & Chemical Names
Cyclohexane-1,3-dione 1,3-Dioxocyclohexane 1,3-CHD m-Dihydroxybenzene dihydride 1,3-dioxo cyclohexane Cyclohexan-1,3-dione Fine chemical building block
Common Names
Dihydroresorcinol 13 CHD Hydroresorcinol
Drug & Sourcing Names
1,3-Cyclohexanedione API Intermediate 1,3-Cyclohexanedione Bulk Drug Phenylhydrazine intermediate Indole synthesis precursor API Starting Material Organic synthesis intermediate
CAS Number
504-02-9
Molecular Formula
C6H8O2 / 112.13 g/mol
Molecular Weight
GC/HPLC Purity (Assay)
≥ 99.5%
Melting Range
104°C - 108°C
Moisture (Karl Fischer)
≤ 0.5%
Residue on Ignition / Ash
≤ 0.1%
Heavy Metals
≤ 10 ppm
Bulk Density
480 kg/m³ - 500 kg/m³
Solubility
Soluble in water, methanol, ethanol, and acetone
Appearance
White to off-white crystalline powder
Packaging & Logistics
25 kg fiber drums with double PE inner bags; custom B2B logistics available
Download Technical Datasheet Request a Quote

Product Overview

1,3-Cyclohexanedione (1,3-CHD / Dihydroresorcinol) is a highly reactive cyclic beta-diketone that exhibits strong keto-enol tautomerism. It is a critical key starting material (KSM) widely used in custom chemical synthesis for anti-emetic pharmaceuticals (such as Ondansetron) and agrochemical herbicides. Sourcing 1,3-Cyclohexanedione from a reliable API Intermediate Manufacturer like Kalpasthana ensures a high-purity product (>=99.0%) that guarantees predictable reaction kinetics and optimal condensation yields during commercial scale manufacturing.

Manufacturing Importance: Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.

Manufacturing Importance

Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.

Applications & Industrial Relevance

1,3-Cyclohexanedione (1,3-CHD / Dihydroresorcinol) is a highly reactive cyclic beta-diketone showing strong keto-enol tautomerism. It is a critical B2B Key Starting Material (KSM) widely used in the pharmaceutical industry for anti-emetic drugs (such as Ondansetron) and beta-blockers (such as Carvedilol), as well as a vital precursor for triketone-based HPPD-inhibitor agrochemical herbicides.

In industrial synthesis, the strong keto-enol tautomerism of 1,3-cyclohexanedione is exploited to form stable enol ethers and amines. Its cyclic 1,3-dicarbonyl structure is essential for forming carbazole rings via condensation, making it a foundation for Ondansetron and Carvedilol synthesis.

Ondansetron Downstream Synthesis

Condensation with phenylhydrazine yields 1,2,3,9-tetrahydrocarbazolone, the direct intermediate required to construct the carbazole core of the anti-emetic API Ondansetron.

Agrochemical HPPD Intermediates

Direct building block for the synthesis of advanced triketone crop protection herbicides such as Mesotrione and Sulcotrione.

Carvedilol Pathway Intermediates

Precursor via tetrahydrocarbazolone to 4-hydroxycarbazole, the essential intermediate for synthesizing the beta-blocker Carvedilol.

Quality Assurance & Process Control

For 1,3-Cyclohexanedione, quality is our foundational pillar. We ensure high-purity diketone building blocks through strict process controls, dry moisture crystallization, and rigorous distillation workflows. Our facility monitors reactions to minimize resorcinol residue and related polymer impurities, guaranteeing batch consistency for Ondansetron KSM and agrochemical (Mesotrione) synthesis.

Every shipment is backed by in-house GC-FID purity verification (maintaining assay purity >=99.0%), moisture content checks, and standard COA profiles to streamline client compliance and B2B audit validation.

Manufactured under strict GMP-compliant standard operating procedures.

In-house analytical testing ensuring HPLC purity >=99.0% for every batch.

Complete B2B regulatory paperwork, technical dossiers, and audit support.

GMP Standards

Manufactured under strict GMP-compliant standard operating procedures.

HPLC Verification

In-house analytical testing ensuring HPLC purity >=99.0% for every batch.

Document Support

Complete B2B regulatory paperwork, technical dossiers, and audit support.

Technical Sourcing Profile

Chemical Synthesis

1,3-Cyclohexanedione (13CHD, Dihydroresorcinol) is a cyclic beta-diketone that undergoes rapid keto-enol tautomerism in solution. It is synthesized industrially via the catalytic hydrogenation of resorcinol under basic conditions or by the condensation of ethyl acetoacetate and methyl acrylate. The resulting white crystalline powder is highly reactive at the active methylene group on C2.

Applications & Pathways

1,3-Cyclohexanedione is a vital Key Starting Material (KSM) in the pharmaceutical industry, reacting with phenylhydrazine to form 1,2,3,9-tetrahydrocarbazolone, the direct precursor for the anti-emetic drug Ondansetron. In agrochemistry, it is the primary building block for synthesizing triketone herbicides such as Mesotrione and Sulcotrione, which inhibit the HPPD enzyme in weeds.

Quality & Compliance

We supply pharmaceutical-grade 1,3-Cyclohexanedione with a GC purity of ≥99.5% and strict controls on moisture content (less than 0.5%) and melting range (104°C - 108°C). Every batch is validated via HPLC/GC analysis to meet global CDMO standards.

Storage & Packaging

It is packed in standard 25 kg fiber drums with double PE inner bags. We offer custom B2B packaging and bulk container logistics from our KIADB Humnabad facility, ensuring moisture-proof and temperature-controlled shipping under 15°C.

Safety & Protocols

Sourcing professionals receive fully validated batch records, Certificates of Analysis (COA), safety data sheets (SDS), and comprehensive EHS hazard analyses. Our plant operates under strict occupational safety guidelines for handling cyclic beta-diketones.

Why Choose Kalpasthana?

High Purity Standards

HPLC purity verified at >=99.0% with minimal related substances.

Reliable Supply Chain

Continuous commercial-scale volume manufacturing capacity.

Robust Technical Support

Complete analytical profiles, GC profiles, MSDS, and COA dossiers.

Advanced Infrastructure

Equipped with a 50 kL combined reactor volume in Karnataka.

Sourcing Compliance & Synonyms

Chemical Synonyms

IUPAC & Chemical Names
Cyclohexane-1,3-dione 1,3-Dioxocyclohexane 1,3-CHD m-Dihydroxybenzene dihydride 1,3-dioxo cyclohexane Cyclohexan-1,3-dione Fine chemical building block
Common Names
Dihydroresorcinol 13 CHD Hydroresorcinol
Drug & Sourcing Names
1,3-Cyclohexanedione API Intermediate 1,3-Cyclohexanedione Bulk Drug Phenylhydrazine intermediate Indole synthesis precursor API Starting Material Organic synthesis intermediate

Manufacturing Location

Kalpasthana Life Care Products, Plot no 105, Part A, KIADB Industrial Area, Humnabad, Bidar District, Karnataka, India - 585330

Compliance & Quality

GMP-compliant state-of-the-art facility, rigorous GC purity standards ≥99.0%.

Commercial Packaging

Standard 25 kg HDPE fiber drums with double polythene inner bags; custom B2B packaging available.

Commercial Sourcing Note

Commercial Sourcing & Synonyms: Sourcing 1,3-Cyclohexanedione under CAS No. 504-02-9 from an established API intermediate manufacturer India ensures standard reaction yields. This diketone is a key Ondansetron intermediate, Carvedilol intermediate, and Mesotrione intermediate. Kalpasthana serves as a reliable Bulk Drug Intermediates supplier India partner, supplying bulk quantities to leading API supplier Hyderabad companies.

Frequently Asked Questions

What synthetic applications exist for 1,3-Cyclohexanedione (CAS 504-02-9)?

1,3-Cyclohexanedione (Dihydroresorcinol) is a highly reactive cyclic 1,3-diketone that exhibits strong keto-enol tautomerism. It is a critical chemical intermediate in the pharmaceutical industry for the production of Ondansetron and other active ingredients. It is also an important building block for modern herbicides and agrochemicals.

What are the quality standards and compliance records for bulk 1,3-Cyclohexanedione?

We supply 1,3-Cyclohexanedione with a GC purity of ≥99.0%. Our quality control team ensures the product meets strict standards for color stability, moisture content, and chemical assay. B2B documentation including COAs, MSDS, and production batch records is provided for every order.

What are the packaging, delivery timelines, and commercial shipping terms for 1,3-Cyclohexanedione?

Standard commercial packaging is 25 kg fiber drums with double polythene inner liners. Sourced directly from our facility in Humnabad, Bidar District, Karnataka, we offer competitive B2B pricing, prompt lead times, and flexible shipping terms (FOB, CIF, etc.) to accommodate global clients.

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1,3-Cyclohexanedione (CAS 504-02-9) Manufacturer India

Home Products 1,3-Cyclohexanedione

High-quality 1,3-Cyclohexanedione (1,3-CHD / 13 CHD / Dihydroresorcinol, CAS 504-02-9), a key intermediate for pharmaceutical and agrochemical synthesis.

Ondansetron intermediate 1,3-Cyclohexanedione CAS 504-02-9 manufacturer India

Bulk 1,3-Cyclohexanedione (1,3-CHD / 13 CHD) CAS 504-02-9 Supplier

CAS No: 504-02-9

1,3-Cyclohexanedione is a highly reactive cyclic beta-diketone that exhibits strong keto-enol tautomerism. It is a critical key starting material used in the synthesis of Ondansetron and various agrochemical herbicides, offering optimal condensation yields.

Product Overview

1,3-Cyclohexanedione (1,3-CHD / Dihydroresorcinol) is a highly reactive cyclic beta-diketone that exhibits strong keto-enol tautomerism. It is a critical key starting material (KSM) widely used in custom chemical synthesis for anti-emetic pharmaceuticals (such as Ondansetron) and agrochemical herbicides. Sourcing 1,3-Cyclohexanedione from a reliable API Intermediate Manufacturer like Kalpasthana ensures a high-purity product (>=99.0%) that guarantees predictable reaction kinetics and optimal condensation yields during commercial scale manufacturing.

Manufacturing Importance: Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.

Technical Specifications

Product Name 1,3-Cyclohexanedione (1,3-CHD)
Synonyms / IUPAC Dihydroresorcinol • Cyclohexane-1,3-dione • 1,3-Dioxocyclohexane • 13 CHD • Hydroresorcinol • 1,3-Cyclohexanedione API Intermediate • 1,3-Cyclohexanedione Bulk Drug • 1,3-CHD • m-Dihydroxybenzene dihydride • 1,3-dioxo cyclohexane • Cyclohexan-1,3-dione • Phenylhydrazine intermediate • Indole synthesis precursor • API Starting Material • Organic synthesis intermediate • Fine chemical building block
CAS Number 504-02-9
Molecular Formula / Wt C6H8O2 / 112.13 g/mol
GC/HPLC Purity (Assay) ≥ 99.5%
Melting Range 104°C - 108°C
Moisture (Karl Fischer) ≤ 0.5%
Residue on Ignition / Ash ≤ 0.1%
Heavy Metals ≤ 10 ppm
Bulk Density 480 kg/m³ - 500 kg/m³
Solubility Soluble in water, methanol, ethanol, and acetone
Appearance White to off-white crystalline powder
Packaging & Logistics 25 kg fiber drums with double PE inner bags; custom B2B logistics available
Request a Technical Quote Download Specs Sheet

Applications & Industrial Relevance

1,3-Cyclohexanedione (1,3-CHD / Dihydroresorcinol) is a highly reactive cyclic beta-diketone showing strong keto-enol tautomerism. It is a critical B2B Key Starting Material (KSM) widely used in the pharmaceutical industry for anti-emetic drugs (such as Ondansetron) and beta-blockers (such as Carvedilol), as well as a vital precursor for triketone-based HPPD-inhibitor agrochemical herbicides.

In industrial synthesis, the strong keto-enol tautomerism of 1,3-cyclohexanedione is exploited to form stable enol ethers and amines. Its cyclic 1,3-dicarbonyl structure is essential for forming carbazole rings via condensation, making it a foundation for Ondansetron and Carvedilol synthesis.

Key Functionalities & Industrial Use Cases

  • Ondansetron Downstream Synthesis: Condensation with phenylhydrazine yields 1,2,3,9-tetrahydrocarbazolone, the direct intermediate required to construct the carbazole core of the anti-emetic API Ondansetron.
  • Agrochemical HPPD Intermediates: Direct building block for the synthesis of advanced triketone crop protection herbicides such as Mesotrione and Sulcotrione.
  • Carvedilol Pathway Intermediates: Precursor via tetrahydrocarbazolone to 4-hydroxycarbazole, the essential intermediate for synthesizing the beta-blocker Carvedilol.

Quality Assurance & Process Control

For 1,3-Cyclohexanedione, quality is our foundational pillar. We ensure high-purity diketone building blocks through strict process controls, dry moisture crystallization, and rigorous distillation workflows. Our facility monitors reactions to minimize resorcinol residue and related polymer impurities, guaranteeing batch consistency for Ondansetron KSM and agrochemical (Mesotrione) synthesis.

Every shipment is backed by in-house GC-FID purity verification (maintaining assay purity >=99.0%), moisture content checks, and standard COA profiles to streamline client compliance and B2B audit validation.

GMP Standards

Manufactured under strict GMP-compliant standard operating procedures.

HPLC Verification

In-house analytical testing ensuring HPLC purity >=99.0% for every batch.

Document Support

Complete B2B regulatory paperwork, technical dossiers, and audit support.

Why Choose Kalpasthana?

Global pharmaceutical sourcing teams partner with Kalpasthana due to our chemical manufacturing expertise, infrastructure reliability, and strict compliance alignment:

  • High Purity Standards: HPLC purity verified at >=99.0% with minimal related substances.
  • Reliable Supply Chain: Continuous commercial-scale volume manufacturing capacity.
  • Robust Technical Support: Complete analytical profiles, GC profiles, MSDS, and COA dossiers.
  • Advanced Infrastructure: Equipped with a 50 kL combined reactor volume in Karnataka.

Technical Sourcing Profile

Chemical Synthesis

1,3-Cyclohexanedione (13CHD, Dihydroresorcinol) is a cyclic beta-diketone that undergoes rapid keto-enol tautomerism in solution. It is synthesized industrially via the catalytic hydrogenation of resorcinol under basic conditions or by the condensation of ethyl acetoacetate and methyl acrylate. The resulting white crystalline powder is highly reactive at the active methylene group on C2.

Applications & Pathways

1,3-Cyclohexanedione is a vital Key Starting Material (KSM) in the pharmaceutical industry, reacting with phenylhydrazine to form 1,2,3,9-tetrahydrocarbazolone, the direct precursor for the anti-emetic drug Ondansetron. In agrochemistry, it is the primary building block for synthesizing triketone herbicides such as Mesotrione and Sulcotrione, which inhibit the HPPD enzyme in weeds.

Quality & Compliance

We supply pharmaceutical-grade 1,3-Cyclohexanedione with a GC purity of ≥99.5% and strict controls on moisture content (less than 0.5%) and melting range (104°C - 108°C). Every batch is validated via HPLC/GC analysis to meet global CDMO standards.

Storage & Packaging

It is packed in standard 25 kg fiber drums with double PE inner bags. We offer custom B2B packaging and bulk container logistics from our KIADB Humnabad facility, ensuring moisture-proof and temperature-controlled shipping under 15°C.

Safety & Protocols

Sourcing professionals receive fully validated batch records, Certificates of Analysis (COA), safety data sheets (SDS), and comprehensive EHS hazard analyses. Our plant operates under strict occupational safety guidelines for handling cyclic beta-diketones.

Sourcing FAQs & Compliance Guide

Quality & Technical Specifications

Chemical Synonyms Cyclohexane-1,3-dione, 1,3-dioxocyclohexane, Dihydroresorcinol
Manufacturing Location Kalpasthana Life Care Products, Plot no 105, Part A, KIADB Industrial Area, Humnabad, Bidar District, Karnataka, India - 585330
Compliance & Quality GMP-compliant state-of-the-art facility, rigorous GC purity standards ≥99.0%.
Commercial Packaging Standard 25 kg HDPE fiber drums with double polythene inner bags; custom B2B packaging available.

Commercial Sourcing & Synonyms: Sourcing 1,3-Cyclohexanedione under CAS No. 504-02-9 from an established API intermediate manufacturer India ensures standard reaction yields. This diketone is a key Ondansetron intermediate, Carvedilol intermediate, and Mesotrione intermediate. Kalpasthana serves as a reliable Bulk Drug Intermediates supplier India partner, supplying bulk quantities to leading API supplier Hyderabad companies.

Frequently Asked Questions

What synthetic applications exist for 1,3-Cyclohexanedione (CAS 504-02-9)?

1,3-Cyclohexanedione (Dihydroresorcinol) is a highly reactive cyclic 1,3-diketone that exhibits strong keto-enol tautomerism. It is a critical chemical intermediate in the pharmaceutical industry for the production of Ondansetron and other active ingredients. It is also an important building block for modern herbicides and agrochemicals.

What are the quality standards and compliance records for bulk 1,3-Cyclohexanedione?

We supply 1,3-Cyclohexanedione with a GC purity of ≥99.0%. Our quality control team ensures the product meets strict standards for color stability, moisture content, and chemical assay. B2B documentation including COAs, MSDS, and production batch records is provided for every order.

What are the packaging, delivery timelines, and commercial shipping terms for 1,3-Cyclohexanedione?

Standard commercial packaging is 25 kg fiber drums with double polythene inner liners. Sourced directly from our facility in Humnabad, Bidar District, Karnataka, we offer competitive B2B pricing, prompt lead times, and flexible shipping terms (FOB, CIF, etc.) to accommodate global clients.

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