4-Hydroxycarbazole
Premium Heterocyclic Intermediate specifically designed for Carvedilol API Production. (CAS 52602-39-8).
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Premium Heterocyclic Intermediate specifically designed for Carvedilol API Production. (CAS 52602-39-8).
Request a Quote
4-Hydroxycarbazole is a pivotal carbazole-based pharmaceutical intermediate manufactured under strict quality controlled manufacturing protocols. It is the direct key starting material (KSM) for the industrial synthesis of Carvedilol, a non-selective beta-blocker. Sourcing high purity pharmaceutical intermediates is essential to eliminate dimer impurities and ensure compliance with pharmacopeial standards. Kalpasthana Life Care Products provides high-purity 4-hydroxycarbazole with reliable batch consistency to meet the demanding requirements of global pharmaceutical chemical manufacturer companies.
Manufacturing Importance: Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.
Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.
4-Hydroxycarbazole is a pivotal heterocyclic intermediate specifically manufactured for the synthesis of Carvedilol, a non-selective beta-blocker/alpha-1 blocker for hypertension and heart failure. Additionally, it serves as a key building block for carbazole-based organic semiconductors, high-performance optical materials, antioxidants, and anti-inflammatory compounds under therapeutic research.
This molecule acts as the direct phenolic precursor in the synthesis of Carvedilol. Its high purity ensures that the subsequent etherification with epichlorohydrin or epoxy-propoxy-carbazole proceeds with minimal side products, preventing the formation of toxic carbazole dimers and maximizing downstream pharmaceutical compliance.
Undergoes selective epoxidation with epichlorohydrin to form epoxy propoxy carbazole, the direct precursor to Carvedilol.
Strictly monitored manufacturing to ensure ultra-low levels of the 2-hydroxy isomer, maximizing downstream chemical yields.
Precursor for photorefractive polymers, holographic materials, and high-stability OLED hole transport layers.
For 4-Hydroxycarbazole, quality is our foundational pillar. We ensure high-purity carbazole derivative footprints through strict process controls, custom vacuum drying, and rigorous isomer filtration. Our facility monitors reactions to minimize trace phenylhydrazine and related metal impurities, guaranteeing batch consistency for beta-blocker API synthesis.
Every commercial shipment of this Carvedilol intermediate is backed by rigorous HPLC purity verification (maintaining assay purity >=99.0%), trace residue analysis, and standard COA profiles to streamline global sourcing and client compliance validation.
Manufactured under strict GMP-compliant standard operating procedures.
In-house analytical testing ensuring HPLC purity >=99.0% for every batch.
Complete B2B regulatory paperwork, technical dossiers, and audit support.
Manufactured under strict GMP-compliant standard operating procedures.
In-house analytical testing ensuring HPLC purity >=99.0% for every batch.
Complete B2B regulatory paperwork, technical dossiers, and audit support.
4-Hydroxycarbazole (9H-carbazol-4-ol) is a phenolic carbazole derivative. It is synthesized industrially by the dehydrogenation and subsequent aromatization of 1,2,3,9-tetrahydrocarbazolone using catalysts like palladium on carbon, or via cyclization reactions of diarylamines.
4-Hydroxycarbazole is the essential Key Starting Material (KSM) for Carvedilol. It reacts with epichlorohydrin to yield 4-(2,3-epoxypropoxy)carbazole (Epoxy Propoxy Carbazole), which is then coupled with 2-(2-methoxyphenoxy)ethylamine to produce the final Carvedilol active ingredient.
Our 4-Hydroxycarbazole features a purity of ≥98.0% by HPLC. Each batch is supplied with an analytical testing certificate.
It is highly sensitive to oxidation and must be packed under nitrogen in sealed containers. Storage in a cool, dark place is mandatory to prevent discoloration.
Wear protective equipment, including gloves, face protection, and respiratory dust masks during transfer operations.
HPLC purity verified at >=99.0% with minimal related substances.
Continuous commercial-scale volume manufacturing capacity.
Complete analytical profiles, GC profiles, MSDS, and COA dossiers.
Equipped with a 50 kL combined reactor volume in Karnataka.
Kalpasthana Life Care Products, Plot no 105, Part A, KIADB Industrial Area, Humnabad, Bidar District, Karnataka, India - 585330
GMP-compliant state-of-the-art facility, rigorous HPLC purity standards ≥99.0%.
Standard 25 kg HDPE fiber drums with double polythene inner bags; custom B2B packaging available.
Commercial Sourcing & Synonyms: Sourcing from a reliable 4-Hydroxycarbazole supplier ensures high reaction yields. This 4-hydroxy carbazole compound is a key Carvedilol API intermediate. Kalpasthana is a premier manufacturer of pharma intermediates, supplying high-quality medicinal chemicals Karnataka and global markets require. We are a trusted Bulk Drug Intermediates supplier India partner.
4-Hydroxycarbazole (also known as 4-Carbazolol or 9H-Carbazol-4-ol) is the direct precursor to Carvedilol, a widely prescribed beta-blocker. The carbazole ring and the hydroxyl group at the 4-position undergo highly selective epoxidation, making it the most cost-effective and chemically stable starting point for this API synthesis.
Kalpasthana ensures a high purity profile for 4-Hydroxycarbazole of ≥99.0% by HPLC. We strictly monitor critical impurities like 2-hydroxycarbazole and other positional isomers to ensure the safety and efficacy of the final API. Full technical packages (MSDS, COA, DMF support) are available for B2B audits.
The compound is packed in 25 kg HDPE fiber drums with double poly-bags. Since it is sensitive to oxidation and light, it must be stored in tightly closed, light-resistant containers. We maintain ready bulk stocks to support long-term supply contracts for global pharmaceutical companies.
4-Hydroxycarbazole is a pivotal carbazole-based pharmaceutical intermediate manufactured under strict quality controlled manufacturing protocols. It is the direct key starting material (KSM) for the industrial synthesis of Carvedilol, a non-selective beta-blocker. Sourcing high purity pharmaceutical intermediates is essential to eliminate dimer impurities and ensure compliance with pharmacopeial standards. Kalpasthana Life Care Products provides high-purity 4-hydroxycarbazole with reliable batch consistency to meet the demanding requirements of global pharmaceutical chemical manufacturer companies.
Manufacturing Importance: Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.
4-Hydroxycarbazole is a pivotal heterocyclic intermediate specifically manufactured for the synthesis of Carvedilol, a non-selective beta-blocker/alpha-1 blocker for hypertension and heart failure. Additionally, it serves as a key building block for carbazole-based organic semiconductors, high-performance optical materials, antioxidants, and anti-inflammatory compounds under therapeutic research.
This molecule acts as the direct phenolic precursor in the synthesis of Carvedilol. Its high purity ensures that the subsequent etherification with epichlorohydrin or epoxy-propoxy-carbazole proceeds with minimal side products, preventing the formation of toxic carbazole dimers and maximizing downstream pharmaceutical compliance.
For 4-Hydroxycarbazole, quality is our foundational pillar. We ensure high-purity carbazole derivative footprints through strict process controls, custom vacuum drying, and rigorous isomer filtration. Our facility monitors reactions to minimize trace phenylhydrazine and related metal impurities, guaranteeing batch consistency for beta-blocker API synthesis.
Every commercial shipment of this Carvedilol intermediate is backed by rigorous HPLC purity verification (maintaining assay purity >=99.0%), trace residue analysis, and standard COA profiles to streamline global sourcing and client compliance validation.
Manufactured under strict GMP-compliant standard operating procedures.
In-house analytical testing ensuring HPLC purity >=99.0% for every batch.
Complete B2B regulatory paperwork, technical dossiers, and audit support.
Global pharmaceutical sourcing teams partner with Kalpasthana due to our chemical manufacturing expertise, infrastructure reliability, and strict compliance alignment:
4-Hydroxycarbazole (9H-carbazol-4-ol) is a phenolic carbazole derivative. It is synthesized industrially by the dehydrogenation and subsequent aromatization of 1,2,3,9-tetrahydrocarbazolone using catalysts like palladium on carbon, or via cyclization reactions of diarylamines.
4-Hydroxycarbazole is the essential Key Starting Material (KSM) for Carvedilol. It reacts with epichlorohydrin to yield 4-(2,3-epoxypropoxy)carbazole (Epoxy Propoxy Carbazole), which is then coupled with 2-(2-methoxyphenoxy)ethylamine to produce the final Carvedilol active ingredient.
Our 4-Hydroxycarbazole features a purity of ≥98.0% by HPLC. Each batch is supplied with an analytical testing certificate.
It is highly sensitive to oxidation and must be packed under nitrogen in sealed containers. Storage in a cool, dark place is mandatory to prevent discoloration.
Wear protective equipment, including gloves, face protection, and respiratory dust masks during transfer operations.
| Chemical Synonyms | 4-Hydroxy-9H-carbazole, 4-Carbazolol, 9H-Carbazol-4-ol, Carvedilol intermediate |
|---|---|
| Manufacturing Location | Kalpasthana Life Care Products, Plot no 105, Part A, KIADB Industrial Area, Humnabad, Bidar District, Karnataka, India - 585330 |
| Compliance & Quality | GMP-compliant state-of-the-art facility, rigorous HPLC purity standards ≥99.0%. |
| Commercial Packaging | Standard 25 kg HDPE fiber drums with double polythene inner bags; custom B2B packaging available. |
Commercial Sourcing & Synonyms: Sourcing from a reliable 4-Hydroxycarbazole supplier ensures high reaction yields. This 4-hydroxy carbazole compound is a key Carvedilol API intermediate. Kalpasthana is a premier manufacturer of pharma intermediates, supplying high-quality medicinal chemicals Karnataka and global markets require. We are a trusted Bulk Drug Intermediates supplier India partner.
4-Hydroxycarbazole (also known as 4-Carbazolol or 9H-Carbazol-4-ol) is the direct precursor to Carvedilol, a widely prescribed beta-blocker. The carbazole ring and the hydroxyl group at the 4-position undergo highly selective epoxidation, making it the most cost-effective and chemically stable starting point for this API synthesis.
Kalpasthana ensures a high purity profile for 4-Hydroxycarbazole of ≥99.0% by HPLC. We strictly monitor critical impurities like 2-hydroxycarbazole and other positional isomers to ensure the safety and efficacy of the final API. Full technical packages (MSDS, COA, DMF support) are available for B2B audits.
The compound is packed in 25 kg HDPE fiber drums with double poly-bags. Since it is sensitive to oxidation and light, it must be stored in tightly closed, light-resistant containers. We maintain ready bulk stocks to support long-term supply contracts for global pharmaceutical companies.
We are a leading API intermediate manufacturer in India, committed to delivering top-quality pharmaceutical and healthcare solutions globally.