Plot no 105, Part A, Karnataka Industrial Area Development Board, Humnabad, Karnataka 585330
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Phenyl Hydrazine Hydrochloride

Industrial Grade Phenyl Hydrazine Hydrochloride High-Purity Reagent for Carvedilol Synthesis and Agrochemicals. (CAS 59-88-1).

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Phenyl Hydrazine Hydrochloride CAS 59-88-1 intermediate manufacturer India
Technical Specifications
Product Name
Phenyl Hydrazine Hydrochloride
Synonyms / Abbreviations
IUPAC & Chemical Names
Phenyl hydrazine Hydrochloride Phenylhydrazine HCl Phenylhydrazinium chloride Hydrazinobenzene Hydrochloride Phenyl hydrazine HCl Phenylhydrazine monohydrochloride Phenylhydrazine chloride Hydrazinobenzene HCl Indole synthesis reagent Dye synthesis starting material Fischer Indole Synthesis Reagent Pharmaceutical reactant Phenylhydrazine HCl Phenyl hydrazine hydrochloride manufacturer
Drug & Sourcing Names
Phenyl Hydrazine Hydrochloride API Phenyl Hydrazine Hydrochloride Bulk Drug Phenyl Hydrazine Hydrochloride API Intermediate Agrochemical intermediate Nitrogen intermediate compound Agrochemical bulk starting material Phenylhydrazine HCl bulk supplier
CAS Number
59-88-1
Molecular Formula
C6H9ClN2 (C6H8N2 · HCl)
Molecular Weight
144.60 g/mol
Purity (Assay by HPLC/Titration)
≥ 99.0%
Melting Range
243°C - 246°C (Dec.)
Residue on Ignition / Ash
≤ 0.1%
Sulfate Content
≤ 0.05%
Solubility
Soluble in water, methanol, and ethanol
Appearance
White to off-white crystalline powder
Commercial Packaging
25 kg fiber drums with double PE inner bag liners
Download Technical Datasheet Request a Quote

Product Overview

Phenyl Hydrazine Hydrochloride is a highly versatile aromatic hydrazine salt widely utilized in the Fischer Indole Synthesis. It serves as a crucial starting material in the synthesis of the entire carbazole pathway for Ondansetron and Carvedilol drug synthesis. Sourcing the hydrochloride salt from Kalpasthana ensures superior chemical stability, reduced volatility, and strict quality controlled manufacturing compared to the free base. We handle worldwide shipping with certified hazardous materials transport compliance.

Manufacturing Importance: Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.

Manufacturing Importance

Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.

Applications & Industrial Relevance

Phenyl Hydrazine Hydrochloride is a highly versatile aromatic hydrazine derivative. It is a legendary reagent for the Fischer Indole Synthesis, making it the primary starting material for the entire carbazole pathway of Carvedilol and Ondansetron. It is also widely used in synthesizing pyrazolone-based anti-inflammatory drugs, organic pigments, dyestuffs, agricultural fungicides, and as an analytical reagent for identifying sugars and carbonyl compounds.

This hydrochloride salt is preferred in industrial pharmaceutical manufacturing over the free base due to its superior stability and reduced volatility. Its high purity is critical for preventing hydrazone-related impurities, which are highly regulated as potentially genotoxic substances in pharmaceutical intermediates.

Carvedilol & Ondansetron Starting Material

Reacts with 1,3-cyclohexanedione to construct the tetrahydrocarbazolone ring for both APIs.

Heterocyclic Reagent

A core reagent for synthesizing pyrazoles, indoles, and pyrazolones in pharmaceutical and agrochemical sectors.

Analytical Characterization

Classic reagent for converting reducing sugars into crystalline osazones and identifying aldehydes/ketones.

Quality Assurance & Process Control

For Phenyl Hydrazine Hydrochloride, quality is our foundational pillar. We ensure high-purity hydrazine salt footprints through strict process controls, specialized hydrochloride salt crystallization, and EHS-compliant closed-loop synthesis. Our facility monitors reactions to minimize sulfate residues and free hydrazine impurities, guaranteeing batch-to-batch consistency for Fischer Indole and agrochemical syntheses.

Every commercial shipment of this hydrazine derivative is backed by in-house titration assay verification (maintaining purity >=99.0%), heavy metal limit testing, and standard COA profiles to support client B2B compliance audits.

Manufactured under strict GMP-compliant standard operating procedures.

In-house analytical testing ensuring HPLC purity >=99.0% for every batch.

Complete B2B regulatory paperwork, technical dossiers, and audit support.

GMP Standards

Manufactured under strict GMP-compliant standard operating procedures.

HPLC Verification

In-house analytical testing ensuring HPLC purity >=99.0% for every batch.

Document Support

Complete B2B regulatory paperwork, technical dossiers, and audit support.

Technical Sourcing Profile

Chemical Synthesis

Phenyl Hydrazine Hydrochloride is a hydrazine derivative. It is synthesized by the diazotization of aniline with sodium nitrite in hydrochloric acid, followed by reduction of the resulting diazonium salt using sodium sulfite or stannous chloride. The hydrochloride salt is precipitated as a stable, white to off-white crystalline powder.

Applications & Pathways

Phenyl Hydrazine HCl is a vital intermediate in the synthesis of heterocyclic compounds. Its primary pharmaceutical application is reacting with 1,3-cyclohexanedione to produce 1,2,3,9-tetrahydrocarbazolone, which is converted to Ondansetron. It is also used in the synthesis of pyrazole derivatives, agrochemicals, and industrial dyes.

Quality & Compliance

We supply premium Phenyl Hydrazine Hydrochloride with a validated purity of ≥99.0% (by titration/HPLC), strict controls on moisture content (≤1.0%), and a melting range of 243°C - 246°C (with decomposition) for robust synthesis yields.

Storage & Packaging

It is packed in standard 25 kg fiber drums with double PE inner bag liners. Store in a dry, cool, well-ventilated warehouse under tight seals, isolated from strong oxidizers, light, and direct heat sources.

Safety & Protocols

As a toxic and potential allergen compound, we handle it under strict EHS protocols. Sourcing teams receive COA, MSDS, and safety data sheets detailing required PPE, ventilation, and dust containment measures.

Why Choose Kalpasthana?

High Purity Standards

HPLC purity verified at >=99.0% with minimal related substances.

Reliable Supply Chain

Continuous commercial-scale volume manufacturing capacity.

Robust Technical Support

Complete analytical profiles, GC profiles, MSDS, and COA dossiers.

Advanced Infrastructure

Equipped with a 50 kL combined reactor volume in Karnataka.

Sourcing Compliance & Synonyms

Chemical Synonyms

IUPAC & Chemical Names
Phenyl hydrazine Hydrochloride Phenylhydrazine HCl Phenylhydrazinium chloride Hydrazinobenzene Hydrochloride Phenyl hydrazine HCl Phenylhydrazine monohydrochloride Phenylhydrazine chloride Hydrazinobenzene HCl Indole synthesis reagent Dye synthesis starting material Fischer Indole Synthesis Reagent Pharmaceutical reactant Phenylhydrazine HCl Phenyl hydrazine hydrochloride manufacturer
Drug & Sourcing Names
Phenyl Hydrazine Hydrochloride API Phenyl Hydrazine Hydrochloride Bulk Drug Phenyl Hydrazine Hydrochloride API Intermediate Agrochemical intermediate Nitrogen intermediate compound Agrochemical bulk starting material Phenylhydrazine HCl bulk supplier

Manufacturing Location

Kalpasthana Life Care Products, Plot no 105, Part A, KIADB Industrial Area, Humnabad, Bidar District, Karnataka, India - 585330

Compliance & Quality

GMP-compliant state-of-the-art facility, rigorous HPLC purity standards ≥99.0%.

Commercial Packaging

Standard 25 kg HDPE fiber drums with double polythene inner bags; custom B2B packaging available.

Commercial Sourcing Note

Commercial Sourcing & Synonyms: Sourcing high-purity Phenyl Hydrazine Hydrochloride under CAS No. 59-88-1 ensures batch-to-batch consistency. Operating as an established hydrazine derivatives manufacturer and Bulk Drug Intermediates supplier India partner, Kalpasthana supplies this key Carvedilol intermediate worldwide.

Frequently Asked Questions

What are the primary industrial applications of Phenyl Hydrazine Hydrochloride (CAS 59-88-1)?

Phenyl Hydrazine Hydrochloride (Phenylhydrazine HCl) is a vital heterocyclic building block. In the pharmaceutical sector, it is a key reagent in the Fischer Indole Synthesis, which is the primary route to create carbazole and indole derivatives, including APIs like Carvedilol. It is also widely used to synthesize agrochemicals, dyes, and organic research compounds.

What are the purity and stability specifications of Kalpasthana's Phenyl Hydrazine Hydrochloride?

Our Phenyl Hydrazine Hydrochloride is a high-grade crystalline material with ≥99.0% purity. We stabilize the salt form to prevent the rapid oxidation that typically occurs with free hydrazine bases. We perform rigorous batch testing to ensure moisture, heavy metals, and free hydrazine levels are strictly minimized.

What storage and safety requirements apply to bulk handling of Phenyl Hydrazine Hydrochloride?

As a toxic and light-sensitive compound, Phenyl Hydrazine Hydrochloride requires careful handling in accordance with international safety regulations. It must be stored in airtight, corrosion-resistant 25 kg drums in a cool, dry area. We provide complete safety guidance, emergency protocols, and fully compliant global logistics.

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Industrial Grade Phenyl Hydrazine Hydrochloride (CAS 59-88-1). High-Purity Reagent for Carvedilol Synthesis and Agrochemicals.

Carvedilol intermediate Phenyl Hydrazine Hydrochloride CAS 59-88-1 manufacturer India

Bulk Phenyl Hydrazine Hydrochloride (Phenylhydrazine HCl) CAS 59-88-1 Supplier

CAS No: 59-88-1

Phenyl Hydrazine Hydrochloride is a versatile aromatic hydrazine salt widely utilized in Fischer Indole Synthesis. It provides superior chemical stability and reduced volatility compared to the free base, optimizing carbazole synthesis for Ondansetron and Carvedilol.

Product Overview

Phenyl Hydrazine Hydrochloride is a highly versatile aromatic hydrazine salt widely utilized in the Fischer Indole Synthesis. It serves as a crucial starting material in the synthesis of the entire carbazole pathway for Ondansetron and Carvedilol drug synthesis. Sourcing the hydrochloride salt from Kalpasthana ensures superior chemical stability, reduced volatility, and strict quality controlled manufacturing compared to the free base. We handle worldwide shipping with certified hazardous materials transport compliance.

Manufacturing Importance: Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.

Technical Specifications

Product Name Phenyl Hydrazine Hydrochloride
Synonyms / IUPAC Phenyl hydrazine Hydrochloride • Phenylhydrazine HCl • Phenylhydrazinium chloride • Hydrazinobenzene Hydrochloride • Phenyl hydrazine HCl • Phenyl Hydrazine Hydrochloride API • Phenyl Hydrazine Hydrochloride Bulk Drug • Phenyl Hydrazine Hydrochloride API Intermediate • Phenylhydrazine monohydrochloride • Phenylhydrazine chloride • Hydrazinobenzene HCl • Indole synthesis reagent • Agrochemical intermediate • Dye synthesis starting material • Fischer Indole Synthesis Reagent • Pharmaceutical reactant Phenylhydrazine HCl • Nitrogen intermediate compound • Agrochemical bulk starting material • Phenyl hydrazine hydrochloride manufacturer • Phenylhydrazine HCl bulk supplier
CAS Number 59-88-1
Molecular Formula C6H9ClN2 (C6H8N2 · HCl)
Molecular Weight 144.60 g/mol
Purity (Assay by HPLC/Titration) ≥ 99.0%
Melting Range 243°C - 246°C (Dec.)
Residue on Ignition / Ash ≤ 0.1%
Sulfate Content ≤ 0.05%
Solubility Soluble in water, methanol, and ethanol
Appearance White to off-white crystalline powder
Commercial Packaging 25 kg fiber drums with double PE inner bag liners
Request a Technical Quote Download Specs Sheet

Applications & Industrial Relevance

Phenyl Hydrazine Hydrochloride is a highly versatile aromatic hydrazine derivative. It is a legendary reagent for the Fischer Indole Synthesis, making it the primary starting material for the entire carbazole pathway of Carvedilol and Ondansetron. It is also widely used in synthesizing pyrazolone-based anti-inflammatory drugs, organic pigments, dyestuffs, agricultural fungicides, and as an analytical reagent for identifying sugars and carbonyl compounds.

This hydrochloride salt is preferred in industrial pharmaceutical manufacturing over the free base due to its superior stability and reduced volatility. Its high purity is critical for preventing hydrazone-related impurities, which are highly regulated as potentially genotoxic substances in pharmaceutical intermediates.

Key Functionalities & Industrial Use Cases

  • Carvedilol & Ondansetron Starting Material: Reacts with 1,3-cyclohexanedione to construct the tetrahydrocarbazolone ring for both APIs.
  • Heterocyclic Reagent: A core reagent for synthesizing pyrazoles, indoles, and pyrazolones in pharmaceutical and agrochemical sectors.
  • Analytical Characterization: Classic reagent for converting reducing sugars into crystalline osazones and identifying aldehydes/ketones.

Quality Assurance & Process Control

For Phenyl Hydrazine Hydrochloride, quality is our foundational pillar. We ensure high-purity hydrazine salt footprints through strict process controls, specialized hydrochloride salt crystallization, and EHS-compliant closed-loop synthesis. Our facility monitors reactions to minimize sulfate residues and free hydrazine impurities, guaranteeing batch-to-batch consistency for Fischer Indole and agrochemical syntheses.

Every commercial shipment of this hydrazine derivative is backed by in-house titration assay verification (maintaining purity >=99.0%), heavy metal limit testing, and standard COA profiles to support client B2B compliance audits.

GMP Standards

Manufactured under strict GMP-compliant standard operating procedures.

HPLC Verification

In-house analytical testing ensuring HPLC purity >=99.0% for every batch.

Document Support

Complete B2B regulatory paperwork, technical dossiers, and audit support.

Why Choose Kalpasthana?

Global pharmaceutical sourcing teams partner with Kalpasthana due to our chemical manufacturing expertise, infrastructure reliability, and strict compliance alignment:

  • High Purity Standards: HPLC purity verified at >=99.0% with minimal related substances.
  • Reliable Supply Chain: Continuous commercial-scale volume manufacturing capacity.
  • Robust Technical Support: Complete analytical profiles, GC profiles, MSDS, and COA dossiers.
  • Advanced Infrastructure: Equipped with a 50 kL combined reactor volume in Karnataka.

Technical Sourcing Profile

Chemical Synthesis

Phenyl Hydrazine Hydrochloride is a hydrazine derivative. It is synthesized by the diazotization of aniline with sodium nitrite in hydrochloric acid, followed by reduction of the resulting diazonium salt using sodium sulfite or stannous chloride. The hydrochloride salt is precipitated as a stable, white to off-white crystalline powder.

Applications & Pathways

Phenyl Hydrazine HCl is a vital intermediate in the synthesis of heterocyclic compounds. Its primary pharmaceutical application is reacting with 1,3-cyclohexanedione to produce 1,2,3,9-tetrahydrocarbazolone, which is converted to Ondansetron. It is also used in the synthesis of pyrazole derivatives, agrochemicals, and industrial dyes.

Quality & Compliance

We supply premium Phenyl Hydrazine Hydrochloride with a validated purity of ≥99.0% (by titration/HPLC), strict controls on moisture content (≤1.0%), and a melting range of 243°C - 246°C (with decomposition) for robust synthesis yields.

Storage & Packaging

It is packed in standard 25 kg fiber drums with double PE inner bag liners. Store in a dry, cool, well-ventilated warehouse under tight seals, isolated from strong oxidizers, light, and direct heat sources.

Safety & Protocols

As a toxic and potential allergen compound, we handle it under strict EHS protocols. Sourcing teams receive COA, MSDS, and safety data sheets detailing required PPE, ventilation, and dust containment measures.

Sourcing FAQs & Compliance Guide

Quality & Technical Specifications

Chemical Synonyms Phenylhydrazine HCl, Hydrazinobenzene hydrochloride, Phenylhydrazinium chloride
Manufacturing Location Kalpasthana Life Care Products, Plot no 105, Part A, KIADB Industrial Area, Humnabad, Bidar District, Karnataka, India - 585330
Compliance & Quality GMP-compliant state-of-the-art facility, rigorous HPLC purity standards ≥99.0%.
Commercial Packaging Standard 25 kg HDPE fiber drums with double polythene inner bags; custom B2B packaging available.

Commercial Sourcing & Synonyms: Sourcing high-purity Phenyl Hydrazine Hydrochloride under CAS No. 59-88-1 ensures batch-to-batch consistency. Operating as an established hydrazine derivatives manufacturer and Bulk Drug Intermediates supplier India partner, Kalpasthana supplies this key Carvedilol intermediate worldwide.

Frequently Asked Questions

What are the primary industrial applications of Phenyl Hydrazine Hydrochloride (CAS 59-88-1)?

Phenyl Hydrazine Hydrochloride (Phenylhydrazine HCl) is a vital heterocyclic building block. In the pharmaceutical sector, it is a key reagent in the Fischer Indole Synthesis, which is the primary route to create carbazole and indole derivatives, including APIs like Carvedilol. It is also widely used to synthesize agrochemicals, dyes, and organic research compounds.

What are the purity and stability specifications of Kalpasthana's Phenyl Hydrazine Hydrochloride?

Our Phenyl Hydrazine Hydrochloride is a high-grade crystalline material with ≥99.0% purity. We stabilize the salt form to prevent the rapid oxidation that typically occurs with free hydrazine bases. We perform rigorous batch testing to ensure moisture, heavy metals, and free hydrazine levels are strictly minimized.

What storage and safety requirements apply to bulk handling of Phenyl Hydrazine Hydrochloride?

As a toxic and light-sensitive compound, Phenyl Hydrazine Hydrochloride requires careful handling in accordance with international safety regulations. It must be stored in airtight, corrosion-resistant 25 kg drums in a cool, dry area. We provide complete safety guidance, emergency protocols, and fully compliant global logistics.

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