Plot no 105, Part A, Karnataka Industrial Area Development Board, Humnabad, Karnataka 585330

Phenyl Hydrazine Hydrochloride (Phenylhydrazine HCl) Manufacturer India

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Industrial Grade Phenyl Hydrazine Hydrochloride (CAS 59-88-1). High-Purity Reagent for Carvedilol Synthesis and Agrochemicals.

Chemical Structure of Phenyl Hydrazine Hydrochloride

Phenyl Hydrazine Hydrochloride (Phenylhydrazine HCl)

CAS No: 59-88-1

A high-purity hydrazine derivative (commonly known as Phenylhydrazine HCl, Phenylhydrazinium Chloride, or Hydrazinobenzene Hydrochloride) widely used as a key building block in pharmaceutical and agrochemical synthesis.

Phenyl Hydrazine Hydrochloride is a critical reagent used in the synthesis of Carvedilol (a prominent beta-blocker), as well as various agrochemicals and dyes. Kalpasthana Life Care Products supplies this compound with guaranteed high purity (99%+) to ensure optimal yield in your downstream manufacturing.

Product Specifications

Product Name Phenyl Hydrazine Hydrochloride
Synonyms / Abbreviations Phenylhydrazine HCl, Hydrazinobenzene hydrochloride, Phenylhydrazinium chloride
CAS Number 59-88-1
Molecular Formula C6H9ClN2
Molecular Weight 144.60 g/mol
Appearance White to Off-white Crystalline Powder
Purity (Titration) ≥ 99.0%
Melting Point 243°C - 246°C (Dec.)

Applications & Usage

Phenyl Hydrazine Hydrochloride is a highly versatile aromatic hydrazine derivative. It is a legendary reagent for the Fischer Indole Synthesis, making it the primary starting material for the entire carbazole pathway of Carvedilol and Ondansetron. It is also widely used in synthesizing pyrazolone-based anti-inflammatory drugs, organic pigments, dyestuffs, agricultural fungicides, and as an analytical reagent for identifying sugars and carbonyl compounds.

Key Features

  • Carvedilol & Ondansetron Starting Material: Reacts with 1,3-cyclohexanedione to construct the tetrahydrocarbazolone ring for both APIs.
  • Heterocyclic Reagent: A core reagent for synthesizing pyrazoles, indoles, and pyrazolones in pharmaceutical and agrochemical sectors.
  • Analytical Characterization: Classic reagent for converting reducing sugars into crystalline osazones and identifying aldehydes/ketones.

Product Specifications & Procurement FAQs

Detailed quality specifications, compliance data, and procurement answers for pharma sourcing professionals.

Quality & Technical Specifications

Chemical Synonyms Phenylhydrazine HCl, Hydrazinobenzene hydrochloride, Phenylhydrazinium chloride
Manufacturing Location Kalpasthana Life Care Products, Plot no 105, Part A, KIADB Industrial Area, Humnabad, Bidar District, Karnataka, India - 585330
Compliance & Quality GMP-compliant state-of-the-art facility, rigorous HPLC purity standards ≥99.0%.
Commercial Packaging Standard 25 kg HDPE fiber drums with double polythene inner bags; custom B2B packaging available.

Frequently Asked Questions

What are the primary industrial applications of Phenyl Hydrazine Hydrochloride (CAS 59-88-1)?

Phenyl Hydrazine Hydrochloride (Phenylhydrazine HCl) is a vital heterocyclic building block. In the pharmaceutical sector, it is a key reagent in the Fischer Indole Synthesis, which is the primary route to create carbazole and indole derivatives, including APIs like Carvedilol. It is also widely used to synthesize agrochemicals, dyes, and organic research compounds.

What are the purity and stability specifications of Kalpasthana's Phenyl Hydrazine Hydrochloride?

Our Phenyl Hydrazine Hydrochloride is a high-grade crystalline material with ≥99.0% purity. We stabilize the salt form to prevent the rapid oxidation that typically occurs with free hydrazine bases. We perform rigorous batch testing to ensure moisture, heavy metals, and free hydrazine levels are strictly minimized.

What storage and safety requirements apply to bulk handling of Phenyl Hydrazine Hydrochloride?

As a toxic and light-sensitive compound, Phenyl Hydrazine Hydrochloride requires careful handling in accordance with international safety regulations. It must be stored in airtight, corrosion-resistant 25 kg drums in a cool, dry area. We provide complete safety guidance, emergency protocols, and fully compliant global logistics.

Technical Profile & Sourcing Guide

Comprehensive chemical specs, catalytic pathways, and quality compliance guidelines for raw materials sourcing.

Chemical Synthesis

Phenyl Hydrazine Hydrochloride is a hydrazine derivative. It is synthesized by the diazotization of aniline with sodium nitrite in hydrochloric acid, followed by reduction of the resulting diazonium salt using sodium sulfite or stannous chloride. The hydrochloride salt is precipitated as a stable, white to off-white crystalline powder.

Applications & Pathways

Phenyl Hydrazine HCl is a vital intermediate in the synthesis of heterocyclic compounds. Its primary pharmaceutical application is reacting with 1,3-cyclohexanedione to produce 1,2,3,9-tetrahydrocarbazolone, which is converted to Ondansetron. It is also used in the synthesis of pyrazole derivatives, agrochemicals, and industrial dyes.

Quality & Compliance

Our Phenyl Hydrazine HCl has a purity of >=99.0% by titration/HPLC, meeting stringent pharmaceutical intermediate specifications.

Storage & Packaging

It is packed in 25 kg fiber drums with double-containment packaging, stored away from strong oxidizers and direct sunlight.

Safety & Protocols

It is a toxic compound and potential allergen, requiring strict EHS protocols, including double-containment, dust masks, and chemical-resistant suits.

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