Alpha Lipoic Acid
High-Purity Alpha Lipoic Acid (Thioctic Acid). A premium organosulfur active pharmaceutical ingredient (API) for dietary supplements and healthcare products. (CAS 1077-28-7).
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High-Purity Alpha Lipoic Acid (Thioctic Acid). A premium organosulfur active pharmaceutical ingredient (API) for dietary supplements and healthcare products. (CAS 1077-28-7).
Request a Quote
Alpha Lipoic Acid (Thioctic Acid) is a universal organosulfur antioxidant widely used in pharmaceutical, nutraceutical, and cosmetic formulations. It acts as an essential cofactor in mitochondrial energy metabolism, offering therapeutic benefits for diabetic neuropathy. Sourcing this active ingredient from Kalpasthana guarantees high purity manufacturing standards (>=99.0% by HPLC) and a stable, free-flowing crystalline powder. Our rigorous quality assurance and analytical testing verify the complete absence of polymer impurities, ensuring maximum bioavailability and shelf life.
Manufacturing Importance: Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.
Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.
Alpha Lipoic Acid (Thioctic Acid) is a premier universal antioxidant and organosulfur compound. It plays a critical role in cellular energy metabolism as a cofactor for mitochondrial multi-enzyme complexes. It is widely formulated in dietary supplements, therapeutic agents for diabetic neuropathy, anti-aging cosmetics, heavy-metal chelators, and neurodegenerative disease treatments.
For bulk pharmaceutical formulations and high-quality nutraceutical products, maintaining a purity of >=99.0% verified by HPLC is essential to ensure maximum bioavailability. The compound's structural integrity is crucial because the five-membered disulfide ring must be highly stable to prevent premature polymerization during encapsulation and storage.
Soluble in both water and fat, allowing it to neutralize free radicals throughout the entire cell structure.
Clinically proven to improve insulin sensitivity and alleviate symptoms of peripheral diabetic neuropathy.
Widely used in topical formulations to prevent photo-aging, reduce skin inflammation, and support collagen structure.
For Alpha Lipoic Acid, quality is our foundational pillar. We ensure USP/EP pharmacopoeia-compliant footprints through strict process controls, light-sensitive handling protocols, and temperature-controlled crystallization lines. Our facility monitors reactions to minimize heavy metal residues and related polymer impurities, guaranteeing batch-to-batch consistency for dietary supplements and anti-oxidant API markets.
Every commercial shipment of this universal antioxidant is backed by rigorous HPLC assay testing, solvent residue analysis, and standard COA profiles to support streamlined client B2B compliance audits.
Manufactured under strict GMP-compliant standard operating procedures.
In-house analytical testing ensuring HPLC purity >=99.0% for every batch.
Complete B2B regulatory paperwork, technical dossiers, and audit support.
Manufactured under strict GMP-compliant standard operating procedures.
In-house analytical testing ensuring HPLC purity >=99.0% for every batch.
Complete B2B regulatory paperwork, technical dossiers, and audit support.
Alpha Lipoic Acid (Thioctic Acid) features a chiral carbon and an eight-carbon fatty acid chain terminated by a 1,2-dithiolane ring. Its industrial synthesis is a multi-step organic process starting with adipate derivatives such as Methyl Adipoyl Chloride. Acylation of ethylene under Friedel-Crafts conditions followed by reduction, thiolation using sodium sulfide, and catalytic ring closure constructs the essential dithiolane ring.
As a universal antioxidant soluble in both water and lipids, Alpha Lipoic Acid is widely formulated in dietary supplements and nutraceuticals to combat oxidative stress. In the pharmaceutical industry, it is a key API used to treat diabetic neuropathy, support cellular energy production, and improve insulin sensitivity. It is also used in advanced anti-aging skincare formulations due to its ability to neutralize free radicals and regenerate other antioxidants.
Our Alpha Lipoic Acid is a light yellow crystalline powder with a purity of >=99.0% verified by HPLC, meeting international USP/EP pharmacopeia standards.
It must be packed in double black polyethylene bags within fiber drums (25 kg) and stored under cool, dark conditions (below 25°C) to prevent thermal degradation.
It is highly sensitive to light, high temperatures, and oxygen, which can cause polymerization of the dithiolane ring. Use safety goggles and gloves.
HPLC purity verified at >=99.0% with minimal related substances.
Continuous commercial-scale volume manufacturing capacity.
Complete analytical profiles, GC profiles, MSDS, and COA dossiers.
Equipped with a 50 kL combined reactor volume in Karnataka.
Kalpasthana Life Care Products, Humnabad, Bidar District, Karnataka, India - 585330
GMP-compliant state-of-the-art facility, rigorous HPLC purity testing, low residue solvents.
Standard commercial fiber drums with double polythene linings; customized B2B sizes.
Commercial Sourcing & Synonyms: For B2B bulk sourcing, this antioxidant API is cataloged under CAS No. 1077-28-7. As a premium Alpha Lipoic Acid manufacturer and Thioctic Acid bulk supplier, Kalpasthana serves global markets from our GMP facility. We are a trusted Bulk Drug Intermediates supplier India exporter.
The industrial synthesis of Alpha Lipoic Acid often starts with Methyl Adipoyl Chloride, which undergoes acylation and reduction to form the carbon skeleton. Subsequent replacement steps introduce the sulfur atoms onto positions 6 and 8, completing the dithiolane ring structure.
Alpha Lipoic Acid is sensitive to light, heat, and oxygen. It must be stored in tightly sealed, light-resistant containers (such as double black poly bags inside fiber drums) at cool temperatures, preferably below 25°C.
We provide comprehensive support for bulk buyers, including detailed Certificates of Analysis (COA) highlighting HPLC assay and heavy metal limits, Material Safety Data Sheet (MSDS), DMF technical packages, and allergen statements for food/supplement compliance.
Alpha Lipoic Acid (Thioctic Acid) is a universal organosulfur antioxidant widely used in pharmaceutical, nutraceutical, and cosmetic formulations. It acts as an essential cofactor in mitochondrial energy metabolism, offering therapeutic benefits for diabetic neuropathy. Sourcing this active ingredient from Kalpasthana guarantees high purity manufacturing standards (>=99.0% by HPLC) and a stable, free-flowing crystalline powder. Our rigorous quality assurance and analytical testing verify the complete absence of polymer impurities, ensuring maximum bioavailability and shelf life.
Manufacturing Importance: Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.
Alpha Lipoic Acid (Thioctic Acid) is a premier universal antioxidant and organosulfur compound. It plays a critical role in cellular energy metabolism as a cofactor for mitochondrial multi-enzyme complexes. It is widely formulated in dietary supplements, therapeutic agents for diabetic neuropathy, anti-aging cosmetics, heavy-metal chelators, and neurodegenerative disease treatments.
For bulk pharmaceutical formulations and high-quality nutraceutical products, maintaining a purity of >=99.0% verified by HPLC is essential to ensure maximum bioavailability. The compound's structural integrity is crucial because the five-membered disulfide ring must be highly stable to prevent premature polymerization during encapsulation and storage.
For Alpha Lipoic Acid, quality is our foundational pillar. We ensure USP/EP pharmacopoeia-compliant footprints through strict process controls, light-sensitive handling protocols, and temperature-controlled crystallization lines. Our facility monitors reactions to minimize heavy metal residues and related polymer impurities, guaranteeing batch-to-batch consistency for dietary supplements and anti-oxidant API markets.
Every commercial shipment of this universal antioxidant is backed by rigorous HPLC assay testing, solvent residue analysis, and standard COA profiles to support streamlined client B2B compliance audits.
Manufactured under strict GMP-compliant standard operating procedures.
In-house analytical testing ensuring HPLC purity >=99.0% for every batch.
Complete B2B regulatory paperwork, technical dossiers, and audit support.
Global pharmaceutical sourcing teams partner with Kalpasthana due to our chemical manufacturing expertise, infrastructure reliability, and strict compliance alignment:
Alpha Lipoic Acid (Thioctic Acid) features a chiral carbon and an eight-carbon fatty acid chain terminated by a 1,2-dithiolane ring. Its industrial synthesis is a multi-step organic process starting with adipate derivatives such as Methyl Adipoyl Chloride. Acylation of ethylene under Friedel-Crafts conditions followed by reduction, thiolation using sodium sulfide, and catalytic ring closure constructs the essential dithiolane ring.
As a universal antioxidant soluble in both water and lipids, Alpha Lipoic Acid is widely formulated in dietary supplements and nutraceuticals to combat oxidative stress. In the pharmaceutical industry, it is a key API used to treat diabetic neuropathy, support cellular energy production, and improve insulin sensitivity. It is also used in advanced anti-aging skincare formulations due to its ability to neutralize free radicals and regenerate other antioxidants.
Our Alpha Lipoic Acid is a light yellow crystalline powder with a purity of >=99.0% verified by HPLC, meeting international USP/EP pharmacopeia standards.
It must be packed in double black polyethylene bags within fiber drums (25 kg) and stored under cool, dark conditions (below 25°C) to prevent thermal degradation.
It is highly sensitive to light, high temperatures, and oxygen, which can cause polymerization of the dithiolane ring. Use safety goggles and gloves.
| Chemical Synonyms | Thioctic acid, 1,2-Dithiolane-3-pentanoic acid, DL-Thioctic acid, DL-alpha-Lipoic acid, Thioctic acid racemic, 6,8-Thioctic acid |
|---|---|
| Manufacturing Location | Kalpasthana Life Care Products, Humnabad, Bidar District, Karnataka, India - 585330 |
| Compliance & Quality | GMP-compliant state-of-the-art facility, rigorous HPLC purity testing, low residue solvents. |
| Commercial Packaging | Standard commercial fiber drums with double polythene linings; customized B2B sizes. |
Commercial Sourcing & Synonyms: For B2B bulk sourcing, this antioxidant API is cataloged under CAS No. 1077-28-7. As a premium Alpha Lipoic Acid manufacturer and Thioctic Acid bulk supplier, Kalpasthana serves global markets from our GMP facility. We are a trusted Bulk Drug Intermediates supplier India exporter.
The industrial synthesis of Alpha Lipoic Acid often starts with Methyl Adipoyl Chloride, which undergoes acylation and reduction to form the carbon skeleton. Subsequent replacement steps introduce the sulfur atoms onto positions 6 and 8, completing the dithiolane ring structure.
Alpha Lipoic Acid is sensitive to light, heat, and oxygen. It must be stored in tightly sealed, light-resistant containers (such as double black poly bags inside fiber drums) at cool temperatures, preferably below 25°C.
We provide comprehensive support for bulk buyers, including detailed Certificates of Analysis (COA) highlighting HPLC assay and heavy metal limits, Material Safety Data Sheet (MSDS), DMF technical packages, and allergen statements for food/supplement compliance.
We are a leading API intermediate manufacturer in India, committed to delivering top-quality pharmaceutical and healthcare solutions globally.