Name: Epoxy propoxy carbazole
Brand: Kalpasthana Life Care Products
SKU: CAS-51997-51-4
Availability: InStock

Epoxy Propoxy Carbazole

CAS No: 51997-51-4

A high-purity crystalline intermediate (commonly referred to as Epoxy Propoxy Carbazole or 4-glycidyloxycarbazole) widely utilized as the key starting material (KSM) in the synthesis of Carvedilol and other carbazole-based pharmaceuticals.

With an active oxirane ring attached to a carbazole nucleus, this compound reacts selectively with nucleophilic amines. Kalpasthana Life Care Products ensures strict limits on residual solvents and enantiomeric purity to support premium pharmaceutical applications.

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Product Specifications

Product Name	Epoxy Propoxy Carbazole
Synonyms / Alternate Names	4-(Oxiran-2-ylmethoxy)-9H-carbazole, 4-Glycidyloxycarbazole, Carvedilol Epoxy Intermediate
CAS Number	51997-51-4
Molecular Formula	C15H13NO2
Molecular Weight	239.27 g/mol
Appearance	White to off-white crystalline solid
Purity (HPLC)	≥ 99.0%
Melting Point	110°C - 114°C

Applications & Usage

Epoxy Propoxy Carbazole (4-(2,3-Epoxypropoxy)carbazole) is a specialized heterocyclic epoxide intermediate. It is the direct key starting material (KSM) for synthesizing the cardiovascular API Carvedilol. Additionally, its highly reactive oxirane ring makes it a valuable building block for specialized high-temperature epoxy resins, thermal-resistant adhesives, and adrenergic receptor ligand research.

Key Features

Carvedilol API Synthesis: Undergoes precise ring-opening condensation with 2-(2-methoxyphenoxy)ethylamine to produce high-purity Carvedilol.
Specialty Epoxy Materials: Used in manufacturing high-performance carbazole-modified epoxy resins with excellent dielectric properties.
Medicinal Chemistry Scaffold: Excellent scaffold for synthesizing compound libraries for cardiovascular and beta-adrenergic studies.

Product Specifications & Procurement FAQs

Detailed quality specifications, compliance data, and procurement answers for pharma sourcing professionals.

Quality & Technical Specifications

Chemical Synonyms	4-(2,3-Epoxypropoxy)carbazole, 4-glycidyloxycarbazole, 4-(oxiranylmethoxy)-9H-carbazole, Epoxy propoxy carbazole
Manufacturing Location	Kalpasthana Life Care Products, Humnabad, Bidar District, Karnataka, India - 585330
Compliance & Quality	GMP-compliant state-of-the-art facility, rigorous HPLC and physical assay testing.
Commercial Packaging	Standard commercial fiber drums or high-barrier protective B2B bags.

Frequently Asked Questions

What amine reactants are typically combined with 4-(2,3-epoxypropoxy)carbazole?

It is mainly reacted with 2-(2-methoxyphenoxy)ethylamine to synthesize Carvedilol. It can also be coupled with other primary or secondary aliphatic amines for library design in medicinal chemistry.

How is the stability of the epoxide group maintained during shipping?

The compound is stable in the solid state under normal ambient warehouse conditions. We package it in dry, moisture-resistant sealed drums to prevent hydrolytic degradation of the oxirane ring.

What are the packaging options and shelf life of Epoxy Propoxy Carbazole?

Epoxy Propoxy Carbazole is typically packaged in 25 kg fiber drums with double PE inner bags. It has a shelf life of 24 months when stored in original, unopened packaging at temperatures below 25°C, away from direct sunlight, heat, and moisture.

Technical Profile & Sourcing Guide

Comprehensive chemical specs, catalytic pathways, and quality compliance guidelines for raw materials sourcing.

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