| Product Name | Methyl 4-acetyl-5-oxohexanoate |
|---|---|
| Synonyms / Alternate Names | 4-Acetyl-5-oxohexanoic acid methyl ester, Methyl 4-acetyl-5-oxohexanoate |
| CAS Number | 13984-53-7 |
| Molecular Formula | C9H14O4 |
| Molecular Weight | 186.21 g/mol |
| Appearance | Colorless to light yellow liquid or low-melting solid |
| Purity (GC) | ≥ 98.0% |
| Boiling Point | 110°C - 114°C at 5 mmHg |
Methyl 4-acetyl-5-oxohexanoate is a highly functionalized tri-carbonyl intermediate widely utilized in heterocyclic chemistry and drug discovery. It is an essential building block for constructing substituted pyrrole rings via modified Knorr and Paal-Knorr condensations. It serves as a key structural scaffold for the synthesis of complex active pharmaceutical ingredients (APIs), including PD-1/PD-L1 pathway inhibitors and agricultural fungicides.
Detailed quality specifications, compliance data, and procurement answers for pharma sourcing professionals.
| Chemical Synonyms | 4-Acetyl-5-oxohexanoic acid methyl ester, Methyl 4-ethanoyl-5-oxo-hexanoate, 4-acetyl-5-keto-hexanoic acid methyl ester, Hexanoic acid, 4-acetyl-5-oxo-, methyl ester, Methyl 4-acetyl-5-oxohexanoate |
|---|---|
| Manufacturing Location | Kalpasthana Life Care Products, Humnabad, Bidar District, Karnataka, India - 585330 |
| Compliance & Quality | GMP-compliant state-of-the-art facility, rigorous GC and analytical purity testing. |
| Commercial Packaging | Standard commercial HDPE drums or customized B2B bottles; custom packaging available. |
It is primarily used to build heterocyclic structures like pyrroles and pyrazoles. Its unique tri-carbonyl structure (two ketones and one ester) allows for highly customized selective condensations and Michael reactions in organic design.
Every batch undergoes GC profiling, density, and moisture control. A comprehensive Certificate of Analysis (COA) is standard with every dispatch from our Humnabad facility.
We pack this product in standard 25 kg plastic carboys or 200 kg steel drums. Because it contains reactive tricarbonyl groups, it should be kept in a cool, dark, dry warehouse in well-sealed containers to prevent moisture absorption and color degradation.
Comprehensive chemical specs, catalytic pathways, and quality compliance guidelines for raw materials sourcing.
Methyl 4-acetyl-5-oxohexanoate is a highly functionalized ester. It is synthesized via the alkylation of methyl acetoacetate or related active methylene compounds. It features multiple carbonyl groups, making it highly reactive.
This compound is used as a specialized intermediate in the synthesis of complex heterocyclic molecules, fine chemicals, and pharmaceutical active ingredients. It is particularly valuable in creating custom chemical scaffolds.
Our compound achieves a purity profile of >=98.0% by GC/HPLC, with full traceability and batch certification.
It is packed in specialized containers and stored in cool, dry environments.
Standard EHS safety protocols and detailed certificates of analysis are provided. Wear gloves and eye protection when transferring.
We are a leading API intermediate manufacturer in India, committed to delivering top-quality pharmaceutical and healthcare solutions globally.