Plot no 105, Part A, Karnataka Industrial Area Development Board, Humnabad, Karnataka 585330
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Benzalkonium Chloride 50% (BKC / ADBAC)

Premium Grade Benzalkonium Chloride 50% (BKC). High-Purity Cationic Surfactant, Biocide, and Disinfectant Active Ingredient. (CAS 8001-54-5).

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Benzalkonium Chloride 50% (BKC / ADBAC) CAS 8001-54-5 intermediate manufacturer India
Technical Specifications
Product Name
Benzalkonium Chloride 50% (BKC / ADBAC)
Synonyms / Abbreviations
IUPAC & Chemical Names
Alkyldimethylbenzylammonium chloride Quaternary Ammonium Compound Benzalkonium chloride (BKC) Alkyl dimethyl benzyl ammonium chloride 50% Quaternary ammonium surfactant Ophthalmic preservative agent BKC 50 manufacturer
Common Names
ADBAC BKC 50 BKC 50% Solution BKC Zephiran Cationic biocide
Drug & Sourcing Names
Benzalkonium Chloride API Benzalkonium Chloride Bulk Drug Antiseptic intermediate
CAS Number
8001-54-5
Molecular Formula
[C6H5CH2N(CH3)2R]Cl (R = C8H17 to C16H33 alkyl chain)
Molecular Weight
Active Content (Assay)
50.0% w/w ± 1.5% w/w (Aqueous Solution)
Free Amines (as Amine HCl)
≤ 1.0%
Refractive Index
1.390 - 1.410 at 20°C
Appearance
Clear, Colorless to Pale Yellow Liquid (mild aromatic odor)
pH (5% aq. solution)
6.0 - 8.0
Density / Specific Gravity
0.980 - 0.995 g/cm³ at 20°C
Solubility
Fully miscible in water, lower alcohols, and acetone
Standard Packaging
Standard 50 kg, 200 kg HDPE drums, or customized IBC totes
Download Technical Datasheet Request a Quote

Product Overview

Benzalkonium Chloride 50% (BKC / ADBAC) is a premium cationic quaternary ammonium surfactant and biocide. It is globally recognized as an essential preservative and antiseptic in ophthalmic, nasal, and topical drug formulations. Manufactured under strict quality controlled manufacturing practices, our BKC solution maintains a precise alkyl chain distribution to optimize antimicrobial efficacy while maintaining high cellular compatibility. Kalpasthana, a leading industrial chemical manufacturer, ensures compliance with global B2B regulatory standards.

Manufacturing Importance: Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.

Manufacturing Importance

Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.

Applications & Industrial Relevance

Benzalkonium Chloride 50% (BKC) is a premium cationic nitrogenous surfactant displaying powerful broad-spectrum biocidal activity at low concentrations. By adsorption onto cell walls and disrupting membrane integrity, BKC targets bacteria, fungi, algae, and enveloped viruses. It is widely used as a primary antiseptic agent, disinfectant raw material, and pharmaceutical preservative in critical health applications.

In topical and ophthalmic drug formulations, Benzalkonium Chloride acts as a critical antimicrobial preservative. It is preferred because of its low-toxicity profile at working concentrations, and sourcing it in a GMP-compliant form ensures the complete absence of heavy metals and alkyl-chain impurities that could compromise cellular compatibility.

Broad-Spectrum Biocidal Efficacy

Destroys microbes via electrostatic interaction with cell membranes, leading to rapid leakage and lysis.

Pharmaceutical-Grade Preservative

The standard antimicrobial preservative for sterile formulations including eye drops, nasal sprays, and antiseptic washes.

Industrial Biocide & Water Treatment

Applied to prevent bio-slimes and algae growth in industrial cooling towers, paper production mills, and swimming pools.

Formulation Compatibility

Highly stable in aqueous solution, compatible with cationic, non-ionic, and amphoteric surfactants.

Quality Assurance & Process Control

For Benzalkonium Chloride 50% (BKC), quality is our foundational pillar. We ensure high-performance surfactant footprints through strict process controls, precise alkyl distribution monitoring, and pH-regulated blending. Our facility tests amine values to minimize free amine impurities, guaranteeing batch-to-batch consistency for pharmaceutical, cosmetic, and disinfectant formulations.

Every shipment is backed by quaternary ammonium active content titration (maintaining ADBAC active content >=50.0%), pH assays, and standard COA profiles to streamline client compliance audits.

Manufactured under strict GMP-compliant standard operating procedures.

In-house analytical testing ensuring HPLC purity >=99.0% for every batch.

Complete B2B regulatory paperwork, technical dossiers, and audit support.

GMP Standards

Manufactured under strict GMP-compliant standard operating procedures.

HPLC Verification

In-house analytical testing ensuring HPLC purity >=99.0% for every batch.

Document Support

Complete B2B regulatory paperwork, technical dossiers, and audit support.

Technical Sourcing Profile

Chemical Synthesis

Benzalkonium Chloride (ADBAC) is synthesized by the reaction of alkyldimethylamine (with alkyl groups ranging from C8 to C18, predominantly C12 and C14) with benzyl chloride under controlled temperature and pressure. The reaction yields a quaternary ammonium salt, which is then dissolved in high-purity water to obtain a stable 50% aqueous solution. The cationic nature of the nitrogen head group gives the compound its active surfactant and cell membrane disrupting capabilities.

Applications & Pathways

In pharmaceutical formulations, BKC 50% is primarily used as an antimicrobial preservative in ophthalmic drops, nasal sprays, and topical creams to prevent microbial growth. In industrial water treatment, it is applied as a highly effective algaecide and biocide in cooling towers, heat exchangers, and swimming pools. It is also an essential disinfectant active ingredient in sanitation products, agricultural disinfection, and food processing hygiene.

Quality & Compliance

Manufactured in our GMP-compliant facility, our BKC 50% aqueous solution is strictly tested for free amines (less than 1%) to prevent skin irritation.

Storage & Packaging

It is stored in robust 50 kg or 200 kg HDPE drums in a well-ventilated, cool environment away from strong oxidizing agents.

Safety & Protocols

Personal protective equipment (PPE) including chemical-resistant gloves and goggles is mandatory during bulk handling due to its concentrated surfactant nature.

Why Choose Kalpasthana?

High Purity Standards

HPLC purity verified at >=99.0% with minimal related substances.

Reliable Supply Chain

Continuous commercial-scale volume manufacturing capacity.

Robust Technical Support

Complete analytical profiles, GC profiles, MSDS, and COA dossiers.

Advanced Infrastructure

Equipped with a 50 kL combined reactor volume in Karnataka.

Sourcing Compliance & Synonyms

Chemical Synonyms

IUPAC & Chemical Names
Alkyldimethylbenzylammonium chloride Quaternary Ammonium Compound Benzalkonium chloride (BKC) Alkyl dimethyl benzyl ammonium chloride 50% Quaternary ammonium surfactant Ophthalmic preservative agent BKC 50 manufacturer
Common Names
ADBAC BKC 50 BKC 50% Solution BKC Zephiran Cationic biocide
Drug & Sourcing Names
Benzalkonium Chloride API Benzalkonium Chloride Bulk Drug Antiseptic intermediate

Manufacturing Location

Kalpasthana Life Care Products, Plot no 105, Part A, KIADB Industrial Area, Humnabad, Bidar District, Karnataka, India - 585330

Compliance & Quality

GMP-compliant facility, rigorously tested for free amines and consistent 50% assay.

Commercial Packaging

Available in 50 kg and 200 kg high-density polyethylene (HDPE) drums.

Commercial Sourcing Note

Commercial Sourcing & Synonyms: Sourcing BKC 50 CAS 8001-54-5 from an established Benzalkonium Chloride 50% manufacturer guarantees GMP compliance. As a premium ADBAC supplier, Kalpasthana supplies this quaternary ammonium biocide, cationic surfactant disinfectant, and cosmetic preservative to global healthcare industries.

Frequently Asked Questions

What are the primary industrial applications of Benzalkonium Chloride 50% (BKC)?

Benzalkonium Chloride 50% (BKC) is a premier cationic surfactant. In the pharmaceutical and personal care sectors, it acts as an active antimicrobial agent in sanitizers, antiseptic wipes, and surgical disinfectants. It is also the most common preservative used in ophthalmic (eye drop) formulations. Industrially, it is used for algae control in cooling water systems.

What are the purity and stability specifications of Kalpasthana's Benzalkonium Chloride 50% (BKC)?

Our Benzalkonium Chloride is supplied as a clear, highly stable 50% aqueous solution. We utilize advanced manufacturing techniques to strictly limit the presence of unreacted free amines to less than 1.0%. Every batch undergoes rigorous quality control for exact assay, pH balance, and color clarity to ensure it meets pharmaceutical preservative standards.

What storage and safety requirements apply to bulk handling of Benzalkonium Chloride 50% (BKC)?

While highly effective at low concentrations, bulk BKC 50% is a concentrated surfactant that requires proper protective equipment during handling to avoid skin and eye irritation. It should be stored in tightly sealed HDPE drums in a well-ventilated, ambient environment away from strong oxidizing agents. We provide full MSDS documentation with every shipment.

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Benzalkonium Chloride 50% (BKC / ADBAC) Manufacturer India

Home Products Benzalkonium Chloride 50% (BKC)

Premium Grade Benzalkonium Chloride 50% (BKC). High-Purity Cationic Surfactant, Biocide, and Disinfectant Active Ingredient.

Preservative BKC 50 Benzalkonium Chloride 50% CAS 8001-54-5 manufacturer

Bulk Benzalkonium Chloride 50% (BKC) CAS 8001-54-5 Supplier

CAS No: 8001-54-5

Benzalkonium Chloride 50% is a premium cationic quaternary ammonium antiseptic and preservative solution. Widely utilized in ophthalmic, nasal, and topical formulations, it is manufactured under strict QC protocols with a precise alkyl chain distribution.

Product Overview

Benzalkonium Chloride 50% (BKC / ADBAC) is a premium cationic quaternary ammonium surfactant and biocide. It is globally recognized as an essential preservative and antiseptic in ophthalmic, nasal, and topical drug formulations. Manufactured under strict quality controlled manufacturing practices, our BKC solution maintains a precise alkyl chain distribution to optimize antimicrobial efficacy while maintaining high cellular compatibility. Kalpasthana, a leading industrial chemical manufacturer, ensures compliance with global B2B regulatory standards.

Manufacturing Importance: Sourced directly from our state-of-the-art facility in Bidar District, Karnataka. Every batch is manufactured under strict quality controlled guidelines, ensuring predictable synthesis yields and batch-to-batch consistency.

Technical Specifications

Product Name Benzalkonium Chloride 50% (BKC / ADBAC)
Synonyms / IUPAC Alkyldimethylbenzylammonium chloride • ADBAC • BKC 50 • Quaternary Ammonium Compound • BKC 50% Solution • Benzalkonium Chloride API • Benzalkonium Chloride Bulk Drug • Benzalkonium chloride (BKC) • BKC • Zephiran • Alkyl dimethyl benzyl ammonium chloride 50% • Quaternary ammonium surfactant • Cationic biocide • Ophthalmic preservative agent • Antiseptic intermediate • BKC 50 manufacturer
CAS Number 8001-54-5
Chemical Formula [C6H5CH2N(CH3)2R]Cl (R = C8H17 to C16H33 alkyl chain)
Active Content (Assay) 50.0% w/w ± 1.5% w/w (Aqueous Solution)
Free Amines (as Amine HCl) ≤ 1.0%
Refractive Index 1.390 - 1.410 at 20°C
Appearance Clear, Colorless to Pale Yellow Liquid (mild aromatic odor)
pH (5% aq. solution) 6.0 - 8.0
Density / Specific Gravity 0.980 - 0.995 g/cm³ at 20°C
Solubility Fully miscible in water, lower alcohols, and acetone
Standard Packaging Standard 50 kg, 200 kg HDPE drums, or customized IBC totes
Request a Technical Quote Download Specs Sheet

Applications & Industrial Relevance

Benzalkonium Chloride 50% (BKC) is a premium cationic nitrogenous surfactant displaying powerful broad-spectrum biocidal activity at low concentrations. By adsorption onto cell walls and disrupting membrane integrity, BKC targets bacteria, fungi, algae, and enveloped viruses. It is widely used as a primary antiseptic agent, disinfectant raw material, and pharmaceutical preservative in critical health applications.

In topical and ophthalmic drug formulations, Benzalkonium Chloride acts as a critical antimicrobial preservative. It is preferred because of its low-toxicity profile at working concentrations, and sourcing it in a GMP-compliant form ensures the complete absence of heavy metals and alkyl-chain impurities that could compromise cellular compatibility.

Key Functionalities & Industrial Use Cases

  • Broad-Spectrum Biocidal Efficacy: Destroys microbes via electrostatic interaction with cell membranes, leading to rapid leakage and lysis.
  • Pharmaceutical-Grade Preservative: The standard antimicrobial preservative for sterile formulations including eye drops, nasal sprays, and antiseptic washes.
  • Industrial Biocide & Water Treatment: Applied to prevent bio-slimes and algae growth in industrial cooling towers, paper production mills, and swimming pools.
  • Formulation Compatibility: Highly stable in aqueous solution, compatible with cationic, non-ionic, and amphoteric surfactants.

Quality Assurance & Process Control

For Benzalkonium Chloride 50% (BKC), quality is our foundational pillar. We ensure high-performance surfactant footprints through strict process controls, precise alkyl distribution monitoring, and pH-regulated blending. Our facility tests amine values to minimize free amine impurities, guaranteeing batch-to-batch consistency for pharmaceutical, cosmetic, and disinfectant formulations.

Every shipment is backed by quaternary ammonium active content titration (maintaining ADBAC active content >=50.0%), pH assays, and standard COA profiles to streamline client compliance audits.

GMP Standards

Manufactured under strict GMP-compliant standard operating procedures.

HPLC Verification

In-house analytical testing ensuring HPLC purity >=99.0% for every batch.

Document Support

Complete B2B regulatory paperwork, technical dossiers, and audit support.

Why Choose Kalpasthana?

Global pharmaceutical sourcing teams partner with Kalpasthana due to our chemical manufacturing expertise, infrastructure reliability, and strict compliance alignment:

  • High Purity Standards: HPLC purity verified at >=99.0% with minimal related substances.
  • Reliable Supply Chain: Continuous commercial-scale volume manufacturing capacity.
  • Robust Technical Support: Complete analytical profiles, GC profiles, MSDS, and COA dossiers.
  • Advanced Infrastructure: Equipped with a 50 kL combined reactor volume in Karnataka.

Technical Sourcing Profile

Chemical Synthesis

Benzalkonium Chloride (ADBAC) is synthesized by the reaction of alkyldimethylamine (with alkyl groups ranging from C8 to C18, predominantly C12 and C14) with benzyl chloride under controlled temperature and pressure. The reaction yields a quaternary ammonium salt, which is then dissolved in high-purity water to obtain a stable 50% aqueous solution. The cationic nature of the nitrogen head group gives the compound its active surfactant and cell membrane disrupting capabilities.

Applications & Pathways

In pharmaceutical formulations, BKC 50% is primarily used as an antimicrobial preservative in ophthalmic drops, nasal sprays, and topical creams to prevent microbial growth. In industrial water treatment, it is applied as a highly effective algaecide and biocide in cooling towers, heat exchangers, and swimming pools. It is also an essential disinfectant active ingredient in sanitation products, agricultural disinfection, and food processing hygiene.

Quality & Compliance

Manufactured in our GMP-compliant facility, our BKC 50% aqueous solution is strictly tested for free amines (less than 1%) to prevent skin irritation.

Storage & Packaging

It is stored in robust 50 kg or 200 kg HDPE drums in a well-ventilated, cool environment away from strong oxidizing agents.

Safety & Protocols

Personal protective equipment (PPE) including chemical-resistant gloves and goggles is mandatory during bulk handling due to its concentrated surfactant nature.

Sourcing FAQs & Compliance Guide

Quality & Technical Specifications

Chemical Synonyms Alkyldimethylbenzylammonium chloride (ADBAC)
Manufacturing Location Kalpasthana Life Care Products, Plot no 105, Part A, KIADB Industrial Area, Humnabad, Bidar District, Karnataka, India - 585330
Compliance & Quality GMP-compliant facility, rigorously tested for free amines and consistent 50% assay.
Commercial Packaging Available in 50 kg and 200 kg high-density polyethylene (HDPE) drums.

Commercial Sourcing & Synonyms: Sourcing BKC 50 CAS 8001-54-5 from an established Benzalkonium Chloride 50% manufacturer guarantees GMP compliance. As a premium ADBAC supplier, Kalpasthana supplies this quaternary ammonium biocide, cationic surfactant disinfectant, and cosmetic preservative to global healthcare industries.

Frequently Asked Questions

What are the primary industrial applications of Benzalkonium Chloride 50% (BKC)?

Benzalkonium Chloride 50% (BKC) is a premier cationic surfactant. In the pharmaceutical and personal care sectors, it acts as an active antimicrobial agent in sanitizers, antiseptic wipes, and surgical disinfectants. It is also the most common preservative used in ophthalmic (eye drop) formulations. Industrially, it is used for algae control in cooling water systems.

What are the purity and stability specifications of Kalpasthana's Benzalkonium Chloride 50% (BKC)?

Our Benzalkonium Chloride is supplied as a clear, highly stable 50% aqueous solution. We utilize advanced manufacturing techniques to strictly limit the presence of unreacted free amines to less than 1.0%. Every batch undergoes rigorous quality control for exact assay, pH balance, and color clarity to ensure it meets pharmaceutical preservative standards.

What storage and safety requirements apply to bulk handling of Benzalkonium Chloride 50% (BKC)?

While highly effective at low concentrations, bulk BKC 50% is a concentrated surfactant that requires proper protective equipment during handling to avoid skin and eye irritation. It should be stored in tightly sealed HDPE drums in a well-ventilated, ambient environment away from strong oxidizing agents. We provide full MSDS documentation with every shipment.

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